Evidence map›Paper›PMID 41743622›Full record

ArticleJournal of ageing and longevity2025

Identifying Older Adults at Risk of Accelerated Decline in Gait Speed and Grip Strength: Insights from the National Health and Aging Trends Study (NHATS).

David H Lynch, Hillary Spangler, Jacob S Griffin, Anna Kahkoska, Dominic Boccaccio, Wenyi Xie, Feng-Chang Lin, John A Batsis, Roger A Fielding

Abstract read
In one paragraph

Article in Journal of ageing and longevity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David H LynchDivision of Geriatric Medicine, Center for Aging and Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-2512-9367
Hillary SpanglerDivision of Geriatric Medicine, Center for Aging and Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0003-4027-4113
Jacob S GriffinDepartment of Anthropology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Anna KahkoskaCenter for Aging and Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Dominic BoccaccioDivision of Geriatric Medicine, Center for Aging and Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-1604-8792
Wenyi XieDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Feng-Chang LinDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-2638-1775
John A BatsisDivision of Geriatric Medicine, Center for Aging and Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-0845-4416
Roger A FieldingDivision of Endocrinology and Metabolism, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SHALENDER BHASIN · 2008 to 2026
$23.9M
Clin-STAR Coordinating CenterU24AG065204 · NIA · AMERICAN FEDERATION FOR AGING RESEARCH · PI Thomas Michael Gill, Kristine Yaffe · 2019 to 2026
$5.5M
Building a Real-World Evidence Base for Continuous Glucose Monitoring in Older Adults with DiabetesK01AG084971 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Anna Rachel Kahkoska · 2024 to 2026
$384k
NCATS NIH HHS UL1 TR002489NCATS NIH HHS UM1 TR004406NIA NIH HHS K01 AG084971NIA NIH HHS P30 AG031679NIA NIH HHS U24 AG065204
6 · The paper itself

Abstract

Gait speed and grip strength are widely used measures of physical function in older adults and are predictive of disability, hospitalization, and mortality. However, there is a limited understanding of the long-term trajectories of these measures and which older adults are at the highest risk of functional decline. We used data from the National Health and Aging Trends Study (NHATS) to identify subgroups of community-dwelling older adults with distinct 10-year trajectories in gait speed and grip strength and to examine the baseline factors associated with these patterns. The sample included 4961 adults aged 65 years and older who completed gait speed and grip strength assessments in 2011 and at least one subsequent wave between 2013 and 2021. Using latent class growth analysis, we identified three trajectories for each measure: worsening, stable, and improving. More than one-third of participants were in the worsening group for at least one measure. In multinomial logistic regression models, lower income, Medicaid coverage, cognitive impairment, and multiple chronic conditions were associated with membership in worsening trajectory groups. These findings highlight the heterogeneity of physical aging and the importance of the early identification of older adults who may benefit from targeted interventions to maintain function and independence over time.

Indexed as

frailtyfunctional declinegait speedgrip strengthNHATSolder adults

Identifiers

PMID41743622
PMCPMC12931739

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.