Evidence map›Paper›PMID 41743361›Full record

ArticleClinical case reports2026

Sequential Amiodarone-Induced Thyroid Dysfunction: From Myxedema Coma to Late-Onset Type 1 Thyrotoxicosis After Drug Withdrawal.

Daniela M Soares, Lia Ferreira

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniela M SoaresEndocrinology Department - Unidade Local de Saúde de Santo António Porto Portugal.ORCID https://orcid.org/0000-0003-4401-2727
Lia FerreiraEndocrinology Department - Unidade Local de Saúde de Santo António Porto Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our report underscores three key points: (1) the prolonged metabolic effects of iodine load and tissue toxicity even after amiodarone cessation, (2) the possibility of reversible amiodarone-induced hypothyroidism preceding subsequent thyrotoxicosis, and (3) the need for long-term thyroid function monitoring, even after amiodarone withdrawal.

Indexed as

amiodarone‐induced hypothyroidismamiodarone‐induced thyroid dysfunctionamiodarone‐induced thyrotoxicosismyxedema coma

Identifiers

PMID41743361
PMCPMC12929177

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.