SynthesisFrontiers in cellular and infection microbiology2026
The effect of gestational weight gain on the infant gut microbiome- a systematic review of the literature.
Synthesis in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Maternal Microbiome in Gestational Diabetes Mellitus: Mechanisms, Biomarkers, and Therapeutic Perspectives.Life (Basel, Switzerland) · 2026Review
- Gut-placenta axis: gut microbiota metabolites may play a role in regulating maternal-fetal immune tolerance and the pathogenesis of adverse pregnancy outcomes.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Maternal weight status and gestational weight gain (GWG) critically affect maternal and neonatal health. The infant gut microbiome is a key predictor of short- and long-term child health. Therefore, investigating how maternal weight characteristics influence the composition and establishment of the infant's gut microbiome is essential. Objective: To evaluate the impact of excessive GWG on the infant gut microbiome. Methodology: PubMed and Scopus were systematically searched for studies on GWG from September 1 Results: A total of 15 studies met the inclusion criteria and were included in this review. Excessive Gestational Weight Gain (EGWG) consistently appeared to impair infant gut microbial alpha diversity, an effect that persisted up to 12 months. Taxonomically, EGWG caused a shift away from beneficial Conclusion: EGWG is an independent, critical determinant of persistent infant gut dysbiosis, characterized by taxonomic and functional shifts. These findings establish EGWG as a key modifiable maternal factor, linking gestational health to infant gut microbiome and health. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251181399, identifier: CRD 420251181399.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.