Evidence map›Paper›PMID 41743356›Full record

ArticleFrontiers in cellular and infection microbiology2026

Human lung organoids model for assessing host response to

Chaofan Li, Pengfei Zhong, Zhimin Yun, Leiming Fang, Meida Xiang, Qisheng Su, Jiru Wang, Hebing Chen, Zhi Chen, Liang Yue and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chaofan Li *Academy of Military Medical Sciences, Beijing, China.
Pengfei Zhong *Academy of Military Medical Sciences, Beijing, China.
Zhimin Yun *Academy of Military Medical Sciences, Beijing, China.
Leiming FangAcademy of Military Medical Sciences, Beijing, China.
Meida XiangAcademy of Military Medical Sciences, Beijing, China.
Qisheng SuDepartment of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jiru WangFaculty of Medicine, Dalian University of Technology, Dalian, China.
Hebing ChenAcademy of Military Medical Sciences, Beijing, China.
Zhi ChenDepartment of Tuberculosis Medicine, Eighth Medical Center, PLA General Hospital, Beijing, China.
Liang YueAcademy of Military Medical Sciences, Beijing, China.
Yingxia TanAcademy of Military Medical Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Airway and alveolar epithelial cells serve as the primary defense in the lower respiratory tract, yet their exact role in Methods: In this study, we established an Results: Prolonged infection led to the gradual invasion of Conclusion: These findings emphasize the potential role of LOs in host defense and demonstrate that the

Indexed as

Host-Pathogen InteractionsLungMycobacterium tuberculosisOrganoidsTuberculosisAntimicrobial PeptidesCytokinesGene Expression ProfilingHumansInduced Pluripotent Stem CellsNF-kappa BToll-Like Receptor 4Antimicrobial PeptidesCytokinesNF-kappa BTLR4 protein, humanToll-Like Receptor 4host-pathogen interactionsinnate immune responselung organoidsTLR4-NF-κB pathwaytuberculosis

Identifiers

PMID41743356
PMCPMC12929407

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.