Evidence map›Paper›PMID 41743328›Full record

ArticleResearch square2026

Stk1 is required for BlaR1-mediated broad-spectrum β-lactam resistance in epidemic-causing strains of

Raymond Poon, Nidhi Satishkumar, Wesley A Mosimann, Vedangi Hayatnagarkar, Vijay Hemmadi, Skyler Kuhn, Aditi Chatterjee, Liam Worrall, Nathan P Manes, J Andrew N Alexander and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Raymond PoonDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD, USA.
Nidhi SatishkumarDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD, USA.
Wesley A MosimannDepartment of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.
Vedangi HayatnagarkarDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD, USA.
Vijay HemmadiDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD, USA.
Skyler KuhnIntegrated Data Sciences Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health; Bethesda, MD, USA.
Aditi ChatterjeeDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD, USA.
Liam WorrallDepartment of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.
Nathan P ManesFunctional Cellular Networks Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
J Andrew N AlexanderDepartment of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.
Justin LackIntegrated Data Sciences Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health; Bethesda, MD, USA.
Henry F ChambersDivision of Infectious Disease, Department of Medicine, San Francisco General Hospital, San Francisco, CA, USA.
Aleksandra Nita-LazarFunctional Cellular Networks Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-8523-605X
Natalie C J StrynadkaDepartment of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia, Vancouver, British Columbia, Canada.
Som S ChatterjeeDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD, USA.ORCID 0000-0002-7138-4449

Funding

Serine/threonine kinase signaling in beta-lactam resistance of Staphylococcus aureusR01AI165510 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Som Chatterjee · 2023 to 2026
$2.8M
NIAID NIH HHS R01 AI165510
6 · The paper itself

Abstract

Sensory induction of

Identifiers

PMID41743328
PMCPMC12930431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.