ArticleObstetrics and gynecology international2026
Effect of Adding Human Umbilical Cord Mesenchymal Stem Cells-Derived Secretome on Sperm Quality Improvement by Swim-Up Method.
Article in Obstetrics and gynecology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effect of Adding Human Umbilical Cord Mesenchymal Stem Cells-Derived Secretome on Sperm Quality Improvement by Swim-Up Method.Obstetrics and gynecology international · 2026Article
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Authors and funding
7 authors.
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Abstract
Background: Suboptimal sperm quality often poses a challenge to successful fertilization. This study hypothesizes that secretome could enhance sperm quality and increase the likelihood of successful pregnancy. This research aims to assess the impact of secretome on various sperm quality parameters, including concentration, motility, and DNA fragmentation, while considering patient-related factors such as age, duration of abstinence, and body mass index (BMI). Method: An analysis involving 45 patients enrolled in the pregnancy program at Halim Fertility Center, Stella Maris Women's and Children's Hospital, Indonesia, from April to September 2023 was conducted. Semen samples from these patients were subjected to the swim-up method and divided into two groups: Group A, which underwent swim-up without secretome, and Group B, which underwent swim-up with the addition of secretome. DNA fragmentation analysis was performed on the sperm swim-up results from both groups. The sperm analysis data obtained before swim-up (pretreatment) with those of Group A and Group B were compared. Result: The demographic data revealed an average age of 37.67 ± 5.36 years, abstinence duration of 4.00 ± 1.15 days, and BMI of 28.20 ± 3.49 kg/m Conclusions: The findings suggest that secretome enhances rapid progressive motility and reduces DNA fragmentation rates without affecting sperm concentration.
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