ArticleFrontiers in medicine2026
Case Report: A rare case of Epstein-Barr virus mucocutaneous ulcers occurring in the eyeball and literature review.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Epstein-Barr virus (EBV)-positive mucocutaneous ulcer (EBVMCU) is a shallow, sharply circumscribed, unifocal mucosal or cutaneous ulcer that often occurs in patients with immunosuppression. Case presentation: We report the case of a 79-year-old woman who underwent left eye keratoplasty for a corneal ulcer and continued topical immunosuppressive therapy after the operation, resulting in left eyeball lesions. Microscopically, the lesion is primarily located in the cornea and extends to the surrounding iris and choroidal tissues. Squamous epithelial ulceration and necrosis with exfoliation on the corneal surface and atypical lymphocytes of various sizes were observed, accompanied by dense polymorphic infiltration of various inflammatory cells, such as small lymphocytes, histiocytes, plasma cells, and eosinophils. These atypical cells had abundant cytoplasm with vesicular chromatin, distinct nucleoli, and scattered large cells resembling Hodgkin and Reed-Sternberg (HRS)-like cells. Immunohistochemistry and Conclusion: To our knowledge, there are no reports of EBVMCU presenting as ocular lesions in the published literature. Therefore, understanding its specificity is very important for the correct diagnosis of this disease and to prevent misdiagnosis and mistreatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.