ArticleFrontiers in nutrition2026
Eating behaviors and liver health in metabolic dysfunction-associated fatty liver disease: the serial mediating roles of Mediterranean diet adherence and adiposity.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This study aimed to investigate the mediating roles of healthy diet adherence and adiposity in the relationship between eating behaviors (uncontrolled or mindful eating) and liver health according to metabolic dysfunction-associated fatty liver disease (MALFD) status. Methods: Adults with and without MAFLD (150 and 90, respectively) were included. Eating behaviors were assessed using the Mindful Eating Questionnaire (MEQ) and Three-Factor Eating Questionnaire (TFEQ), and Mediterranean diet adherence was measured with the Mediterranean Diet Adherence Screener (MEDAS). Adiposity indices included Body Mass Index (BMI) and Visceral Adiposity Index (VAI). Liver health markers were alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Statistical analyses comprised group comparisons, Spearman correlations, and serial mediation models tested using Hayes' PROCESS macro. Results: Individuals with MAFLD had higher BMI (median 32 vs. 25 kg/m Conclusion: The results support the presence of indirect associations linking eating behavior scores to liver enzyme levels via Mediterranean diet adherence and adiposity, particularly in the context of MAFLD. These pathways point to potentially modifiable behavioral and dietary targets, while underscoring the need for confirmation through prospective and interventional studies.
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