SynthesisFrontiers in neurology
Effects of acupuncture on brain tissue metabolism and neurological function in patients with ischemic stroke: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to explore the effects of acupuncture on brain tissue metabolism and neurological function in regions centers of patients with ischemic stroke (IS). Methods: From the establishment of the database until May 20, 2025, a comprehensive search was conducted across several databases, including CNKI, WanFang, VIP Database, CBM, PubMed, Cochrane Library, Embase, and Web of Science. This search specifically targeted clinical randomized controlled trials (RCTs) that investigated the effects of acupuncture on cerebral tissue metabolism within the center of IS lesions and its subsequent impact on neurological function. The literature was meticulously screened, and information was extracted in accordance with the PRISMA guidelines. The quality of the literature was assessed using the risk of bias scale recommended in the Cochrane Handbook for Systematic Reviews of Interventions, version 5.1.0. Additionally, the quality of the included literature and the meta-analysis were evaluated using RevMan 5.4. Results: This study included 9 randomized controlled trials involving 602 patients. The meta-analysis results indicate that acupuncture treatment significantly improves the NAA/Cr ratio [MD = 0.19, 95% CI (0.14-0.24), Conclusion: Adding acupuncture therapy to conventional treatment improves brain tissue metabolism and neurological function in patients with IS. It shows better efficacy compared to conventional treatment alone. However, evidence for specific outcome measures is limited. High-quality, large-scale RCTs are needed to strengthen the evidence base. Systematic review registration: https://www.crd.york.ac.uk/, CRD42024579263.
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