Evidence map›Paper›PMID 41743050›Full record

ArticleFrontiers in neurology

Diagnostic accuracy of venous manometry to predict elevated intracranial pressure.

Timothy White, Kevin Shah, Brendan Ryu, Shyle Mehta, Justin Turpin, Jared Bassett, Brianna Donnelly, Kadir Ozler, Miriam Shao, Cassidy Werner and 6 more

Abstract read
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Timothy WhiteDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Kevin ShahDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Brendan RyuDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Shyle MehtaDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Justin TurpinDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Jared BassettDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Brianna DonnellyDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Kadir OzlerDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Miriam ShaoDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Cassidy WernerDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Kyriakos PapadimitriouDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Golnaz MoazamiDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Jamie MitchellDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Robert RothsteinNew York Eye and Ear Infirmary of Mount Sinai, New York, NY, United States.
Howard PomeranzDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.
Athos PatsalidesDonald and Barbara Zucker School of Medicine, Hofstra University, Hempstead, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Venous sinus stenting (VSS) is a well-established treatment for idiopathic intracranial hypertension (IIH). Diagnostic workup includes lumbar puncture (LP) for intracranial pressure (ICP) measurement and catheter venography with manometry to assess venous sinus stenosis. We evaluated the diagnostic accuracy of venous manometry in predicting elevated ICP. Materials and methods: We retrospectively reviewed patients with venous sinus stenosis who underwent catheter cerebral venography with venous pressure (mmHg) recording and fluoroscopy-guided LP with cerebrospinal fluid opening pressure (CSF-OP, cmH₂O) measurement during the same session. Elevated ICP was defined as CSF-OP ≥20 cmH₂O. Linear regression assessed relationships between venous pressures, trans-stenotic gradient (TSG), and CSF-OP. Sensitivity, specificity, and receiver operating characteristic (ROC) analyses were performed. Results: 84 female patients (mean age 35.5 years) with ≥50% stenosis of the dominant or codominant lateral venous sinuses were included. TSG demonstrated the strongest correlation with CSF-OP (adjusted R Conclusion: SSS pressure and TSG strongly predict ICP elevation in venous sinus stenosis, with combined thresholds providing the highest diagnostic accuracy.

Indexed as

idiopathic intracranial hypertension (IIH)intracranial pressure (ICP)lumbar puncture (LP)venous manometryvenous sinus stenosisvenous sinus stenting (VSS)

Identifiers

PMID41743050
PMCPMC12929161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.