ArticleAmerican heart journal plus : cardiology research and practice2026
Effects of pericardial incision on circulation and body oxygenation in pediatric patients with congenital heart disease.
Article in American heart journal plus : cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Study objective: To evaluate the influence of pericardial incision (PI) on circulation and body oxygenation and identify factors influencing them in pediatric patients undergoing surgery for congenital heart disease (CHD). Design: Prospective observational study. Setting: Gunma Children's Medical Center from August 4, 2022 to May 30, 2025. Participants: We evaluated 63 patients aged 0-18 years with CHD undergoing elective cardiovascular surgery. Main outcome measures: Blood pressure (BP), central venous pressure (CVP), and tissue oxygenation index (TOI), representing systemic oxygenation, were measured before and after PI during surgery and compared between the pre- and post-incision periods. Univariate (logistic) regression analysis was performed with the age and type of disease set as explanatory variables. Results: Systolic (sBP), diastolic (dBP), and mean blood pressure (mBP) significantly decreased after PI. CVP significantly increased from 4.93 (1.96) to 6.08 (2.47), Conclusion: PI increases venous congestion and reduces arterial pressure, leading to a decline in systemic oxygenation in patients with CHD. Therefore, age exhibits the most detrimental effect on this pathological condition.
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