Evidence map›Paper›PMID 41742947›Full record

ArticleFrontiers in surgery2026

Retrospective cohort study: stereotactic aspiration of necrotic tissue versus conservative medical management for malignant MCA infarction.

Xi Zhang, Yao Zhang, Quan Chen, Hang Wu, Yijun Deng, Aidong Zheng, Hongtian Zhang, Maogang Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xi Zhang *The Center of Stroke, Affiliated Hospital 6 of Nantong University, Medical School of Nantong Univeisity, Nantong, JiangSu, China.
Yao Zhang *Department of Neurology, Pukou Hospital of Chinese Medicine Affiliated to China Pharmaceutical University, Nanjing, JiangSu, China.
Quan Chen *Department of Neurology, Huai'an First People's Hospital, Huai'an, JiangSu, China.
Hang WuDepartment of Neurology, Affiliated Hospital 6 of Nantong University, Yancheng Third People's Hospital, Yancheng, JiangSu, China.
Yijun DengDepartment of Emergency, Yancheng Clinical College of Xuzhou Medical University, Yancheng No.1 People's Hospital, Yancheng, JiangSu, China.
Aidong ZhengDepartment of Emergency, Jianhu People's Hospital, Yancheng, JiangSu, China.
Hongtian ZhangDepartment of Neurosurgery, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.
Maogang ChenThe Center of Stroke, Affiliated Hospital 6 of Nantong University, Medical School of Nantong Univeisity, Nantong, JiangSu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to investigate the efficacy and safety of stereotactic aspiration of necrotic brain tissue in patients aged 61 years and older with malignant middle cerebral artery infarction (MMI). Methods: A total of 121 MMI patients aged 61 years and older were enrolled retrospectively in this cohort. They were subjected to conservative medical treatment alone or in addition to stereotactic aspiration of necrotic brain tissue between 24 and 72 h after symptom onset. Perioperative outcomes and 6-month follow-up outcomes were observed and evaluated. Results: Baseline characteristics were well balanced between the conservative treatment group and the aspiration group, except for a higher prevalence of hypertension in the conservative group. The incidence of early cerebral herniation (8.5% vs. 47.3%, Conclusion: The study showed stereotactic aspiration of necrotic brain tissue could be effective and safe for the elderly patients with MMI.

Indexed as

decompressive hemicraniectomylarge hemispheric infarctionmalignant cerebral middle artery infarctionstereotactic aspirationthe elderly

Identifiers

PMID41742947
PMCPMC12929484

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.