Trends and Determinants of Blood Pressure Control in US Hypertensive Patients: Insights from NHANES 1999-2021.

Yiming Shi, Ke Xie, Zhichen Xu, Jingyi Zhang, Lei Liu

Abstract read

In one paragraph

Article in Missouri medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yiming ShiCenter for Biostatistics and Data Science, Washington University School of Medicine, St. Louis, Missouri, USA.

Ke XieCenter for Biostatistics and Data Science, Washington University School of Medicine, St. Louis, Missouri, USA.

Zhichen XuDepartment of Statistics and Data Science, Washington University, St. Louis, Missouri, USA.

Jingyi ZhangDepartment of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.

Lei LiuCenter for Biostatistics and Data Science, Washington University School of Medicine, St. Louis, Missouri, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study analyzes trends and determinants of blood pressure control among hypertensive patients in the United States (US) using National Health and Nutrition Examination Survey NHANES data from 1999 to 2021. Blood pressure control rates improved through 2013 but declined thereafter. Applying machine learning methods such as XGBoost, we identify hypertension awareness and antihypertensive medication use as the strongest predictors of successful control. In contrast, resistant hypertension, chronic kidney disease, and elevated low-density lipoprotein (LDL) levels are associated with poorer control. The shift from JNC7 to JNC8 hypertension guidelines reclassified some individuals from uncontrolled to controlled, influencing observed trends. Additionally, a reduction in antihypertensive medication use among female patients may have contributed to the recent decline. These findings highlight the critical role of medication adherence and patient awareness in maintaining blood pressure control.

Indexed as

Blood Pressure ControlHypertensionMachine LearningTime Trend Analysis

Identifiers

PMID41742927

PMCPMC12931589

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.