Evidence map›Paper›PMID 41742906›Full record

ArticleRadiology case reports2026

Multifocal micronodular pneumocyte hyperplasia in the absence of tuberous sclerosis complex: A case report.

Tomonori Chikasue, Yoshiaki Zaizen, Saeko Tokisawa, Akiko Sumi, Masahiro Mitsuoka, Jun Akiba, Yumi Shioyama, Shuji Nagata, Shuichi Tanoue, Kiminori Fujimoto

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tomonori ChikasueDepartment of Radiology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Yoshiaki ZaizenDivision of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Saeko TokisawaDepartment of Pathology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Akiko SumiDepartment of Radiology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Masahiro MitsuokaDepartment of Surgery, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Jun AkibaDepartment of Pathology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Yumi ShioyamaDepartment of Radiology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Shuji NagataDepartment of Radiology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Shuichi TanoueDepartment of Radiology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Kiminori FujimotoDepartment of Radiology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multifocal micronodular pneumocyte hyperplasia (MMPH) is rare in the absence of tuberous sclerosis complex (TSC). We report a genetically confirmed TSC-negative case in a 50-year-old male patient with numerous bilateral ill-defined ground-glass nodules found on chest computed tomography. The nodules were distributed predominantly in the upper and middle lung zones and showed a centrilobular distribution. The nodules measured 1-15 mm in diameter, and some abutted pleural surfaces. Because several nodules showed slight enlargement (1-2 mm) over 1 year, a diagnostic surgical biopsy was performed. Histopathology confirmed MMPH, showing a single layer of type II pneumocyte proliferation with intra-alveolar macrophages. This case demonstrates that extensive hyperplasia in MMPH can cause lesions to contact the interlobar or visceral pleura, which may be mistaken for lymphangitic spread on computed tomography, and highlights the importance of histopathological correlation to clarify imaging findings.

Indexed as

Multifocal micronodular pneumocyte hyperplasiaMultiple pulmonary nodulesPathologyTomography, X-ray computedTuberous sclerosis

Identifiers

PMID41742906
PMCPMC12930075

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.