Trial reportJournal of periodontology2026
The effect of bioactive membrane in alveolar ridge preservation: A double-blind randomized clinical trial.
Trial report in Journal of periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Effect of Membrane Perforations With and Without Collagen Membrane Coverage in Vertical Ridge Augmentation: An Experimental Pilot In Vivo Study.Clinical oral implants research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundThis randomized controlled trial aims to evaluate alveolar ridge preservation (ARP) with or without a biologically active amnion-chorion membrane (BACM).
methodsThirty patients requiring tooth extraction in the esthetic zone were randomly assigned to 2 groups. Both groups underwent tooth extraction and collagenated bovine bone grafting, while the test sites received an additional BACM. Cone-beam computed tomography (CBCT) and intraoral scans (IOS) were performed before extraction and at 4 months post-extraction. Patient-reported outcomes (PROs) were assessed. The primary endpoint was the change in vertical and horizontal hard and soft tissue dimensions as measured by CBCT and clinically.
resultsAll patients completed implant placement. CBCT measurements at 2 mm demonstrated that control and test groups exhibited reductions in horizontal ridge width with median decreases of 1.19 mm and 2.41 mm, respectively, with no significant differences (p = 0.126). For vertical height changes, the control and test groups experienced mean reductions of 0.99 ± 1.08 mm and 1.33 ± 0.73 mm, respectively, with no significant differences (p = 0.250). IOS analyses showed that mean soft tissue thickness at the alveolar crest was 2.67 ± 0.699 mm (p = 0.370) in the control versus 2.13 ± 0.807 mm (p = 0.846) in the test group, with no significant differences (p = 0.325).
conclusionThe addition of a BACM did not improve the mean horizontal or vertical bone dimentional changes or have a measurable effect on the soft tissue outcome during ARP.
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Registered trials
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