Evidence map›Paper›PMID 41742803›Full record

ArticleBiotechnology and applied biochemistry2026

Constructing Haloarchaeal MVA Pathway in Serratia marcescens for Synthesis of Ocimene.

Songsong Yao, Di Liu, Long Wang, TaiPing Fan, Huaxiang Deng, Yujie Cai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biotechnology and applied biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Songsong YaoThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China.
Di LiuThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China.
Long WangThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China.
TaiPing FanDepartment of Pharmacology, University of Cambridge, Cambridge, UK.
Huaxiang DengCollege of Food Science and Engineering, Jilin University, Changchun, Jilin, China.
Yujie CaiThe Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ocimene, a valuable monoterpene with applications in agriculture, pharmaceuticals, and fragrances, is challenging to produce at high yields using traditional microbial platforms such as Escherichia coli and Saccharomyces cerevisiae due to monoterpene toxicity. In this study, Serratia marcescens, known for its tolerance to organic solvents and terpenes, was engineered to synthesize ocimene through the haloarchaeal mevalonate (MVA) pathway. We optimized key enzymes, promoters, and pathway construction to enhance production. The engineered strain successfully produced ocimene, with a yield of 436 mg·L

Indexed as

Mevalonic AcidSerratia marcescensMevalonic Acidhaloarchaeal mevalonate pathwayocimeneSerratia marcescensstrain construction

Identifiers

PMID41742803
PMCPMC13446408

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.