Evidence map›Paper›PMID 41742575›Full record

ArticleJournal of veterinary internal medicine2026

Longitudinal study of diet digestibility, microbiome, and gut fermentation metabolites in growing dogs.

Eduarda L Fernandes, Renata B M S Souza, Lorenna N A Santos, Laiane S Lima, Heloísa L Silva, Simone G Oliveira, Ananda P Félix

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eduarda L FernandesDepartment of Animal Science, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba, Paraná 80035-050, Brazil.ORCID 0009-0006-1059-0835
Renata B M S SouzaDepartment of Animal Science, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba, Paraná 80035-050, Brazil.ORCID 0000-0001-6621-1116
Lorenna N A SantosDepartment of Animal Science, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba, Paraná 80035-050, Brazil.ORCID 0009-0006-1642-0810
Laiane S LimaDepartment of Animal Science, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba, Paraná 80035-050, Brazil.ORCID 0009-0000-1558-713X
Heloísa L SilvaDepartment of Animal Science, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba, Paraná 80035-050, Brazil.ORCID 0000-0001-9053-4804
Simone G OliveiraDepartment of Animal Science, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba, Paraná 80035-050, Brazil.ORCID 0000-0002-2913-1173
Ananda P FélixDepartment of Animal Science, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba, Paraná 80035-050, Brazil.ORCID 0000-0002-8570-5725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPuppies have particular characteristics due to gastrointestinal immaturity, influencing physiological processes. HYPOTHESIS/

objectivesEvaluate the effects of age and consumption on apparent diet digestibility coefficients (ADC), fecal characteristics, fermentation metabolites, and fecal microbiome in growing dogs. ANIMALS: Eight dogs were evaluated at 2, 5, 8, 11, and 14 months old in experiment 1 and 12 dogs at 14 months old in experiment 2.

methodsThis was a prospective experimental study. Dietary ADC, fecal characteristics, fermentation metabolites, and fecal microbiome were evaluated in 2 experiments: the first analyzed the effect of age, and the second, the effect of consumption in 2 groups: adult intake (AI) and puppy intake (PI).

resultsOlder dogs had lower ADC of dry matter (DM), ether extract, and metabolizable energy, and higher ADC of crude protein (CP) (P < .05). Younger dogs had lower fecal DM and fecal score and higher fecal production (P < .05). Older dogs had higher fecal concentrations of short-chain fatty acids and indoles and lower concentrations of branched-chain fatty acids (BCFA) (P < .05). Dogs aged between 2 and 5 months had a higher fecal abundance of Streptococcus and Escherichia coli and lower abundance of Turicibacter and Peptacetobacter (P < .05). The ADC of DM, organic matter, and CP were lower in PI dogs than in AI dogs (P < .05). The AI dogs had higher fecal DM and fecal score and lower fecal production (P < .05). Puppy intake dogs had higher fecal concentrations of ammonia and BCFA and a higher abundance of Streptococcus and a lower abundance of Blautia (P < .05). CONCLUSIONS AND CLINICAL IMPORTANCE: Age and feed intake influence the ADC of nutrients and energy, the fecal microbiome, and fermentation metabolites, with the microbiota stabilizing after 8 months of age in dogs.

Indexed as

ageconsumptionintestinal functionalitypuppies

Identifiers

PMID41742575
PMCPMC12900069

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.