ArticleJournal of veterinary internal medicine2026
Correlation between cerebellar lesion topography and differential diagnosis with clinical presentation in dogs.
Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCerebellar diseases in dogs cause diverse neurologic signs depending on the affected region. Although functional topographic maps linking cerebellar areas to motor, behavioral, and vestibular functions have been established in humans, such mapping is poorly characterized in veterinary medicine. HYPOTHESIS/
objectivesEvaluate how specific clinical signs in dogs correspond to cerebellar lesion locations and contribute to differential diagnoses. ANIMALS: One hundred two client-owned dogs from 4 referral centers in Spain and the United Kingdom.
methodsMulticenter retrospective study including dogs diagnosed with cerebellar disease that underwent neurologic examination and magnetic resonance imaging of the head.
resultsRostral cerebellar lobe lesions were significantly associated with motor abnormalities: the rostral culmen with cerebellar ataxia (OR, 5.76) and the lobulus centralis with decerebellate rigidity (OR, 5.68). Caudal lobe involvement (folium and tuber vermis) was linked to abnormal behavior (OR, 4.12). Deep white matter lesions involving the interpositus nucleus were associated with head tilt (OR, 6.48), nystagmus (OR, 3.76), vestibular ataxia (OR, 4.01), and delayed postural reactions (OR, 4.83).Vascular disease was significantly associated with brachycephalic breeds (P = .02), comorbidities (P < .001), non-ambulation (P = .01), and paresis (P = .01). Neoplasia was significantly linked to incoordination (P = .02), head tilt (P < .01), and abnormal behavior (P < .001). Inflammatory or infectious diseases commonly presented with pain (P = .02) and tremors (P < .001). CONCLUSION AND CLINICAL IMPORTANCE: Our findings suggest 3 region-related cerebellar syndromes in dogs, motor (rostral lobe), behavioral (caudal lobe), and vestibular (deep white matter), which parallel cerebellar syndromes described in humans. Additionally, the specific clinical presentation may indicate a particular differential diagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.