Evidence map›Paper›PMID 41742548›Full record

ArticleJournal of veterinary internal medicine2026

Monocular ictal nystagmus in a dog: potentially a newly recognized focal seizure phenotype.

João Miguel De Frias, Elsa Lyon, Albert Aguilera-Padros, Aran Nagendran

Abstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

João Miguel De FriasThe Royal (Dick) School of Veterinary Studies Hospital for Small Animals, University of Edinburgh, Edinburgh EH25 9RG, United Kingdom.ORCID 0000-0001-5508-7666
Elsa LyonElyope, 94100 Saint-Maur-des-Fossés, France.
Albert Aguilera-PadrosThe Royal (Dick) School of Veterinary Studies Hospital for Small Animals, University of Edinburgh, Edinburgh EH25 9RG, United Kingdom.ORCID 0009-0008-8537-5704
Aran NagendranThe Royal (Dick) School of Veterinary Studies Hospital for Small Animals, University of Edinburgh, Edinburgh EH25 9RG, United Kingdom.ORCID 0000-0002-8705-8576

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 3-year-old, male neutered toy Chinese crested powderpuff dog was presented with an acute onset obtundation that progressed to status epilepticus. On presentation, neurological examination was localized to a right forebrain lesion. Bizarre episodes, consisting of disconjugate nystagmus of the left eye, medial strabismus of the right eye with convergent-retraction movements in both eyes, were recorded. Head magnetic resonance imaging revealed intra-axial multifocal lesions affecting the right fronto-temporal cortices and dorsal paramedian thalamus. Cerebrospinal fluid analysis revealed a marked mononuclear pleocytosis. Electroencephalographic recordings revealed recurrent medium-amplitude interictal isolated spikes, and suspected epileptic spikes alongside with eye movement that were mainly visible in the right hemisphere. The presumptive diagnosis was meningoencephalitis of unknown origin. Despite treatment, the dog died. This is a report of monocular nystagmus with a presumptive epileptic origin in veterinary medicine, a rare clinical sign in human patients.

Indexed as

Dog DiseasesNystagmus, PathologicSeizuresAnimalsDogsElectroencephalographyFatal OutcomeMagnetic Resonance ImagingMaleStatus Epilepticuscaninefocal seizuresaccadic eye movementvestibular epilepsy

Identifiers

PMID41742548
PMCPMC12881959

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.