ArticleJournal of veterinary internal medicine2026
Perioperative assessment of electroencephalography in dogs with congenital portosystemic shunts.
Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundBiomarkers to identify dogs at risk of developing seizures after surgical attenuation of congenital portosystemic shunts (CPS) have not been defined. HYPOTHESIS/
objectivesTo prospectively characterize perioperative electroencephalographic findings in dogs with CPS undergoing shunt attenuation, and to evaluate their association with outcomes after attenuation. ANIMALS: Twenty-eight client-owned dogs with CPS enrolled prospectively.
methodsA prospective cohort of dogs presenting with no overt signs of encephalopathy underwent ambulatory electroencephalography (EEG) before and after CPS attenuation. Electroencephalography background activity and presence of epileptiform or encephalopathic features were assessed qualitatively. Quantitative analysis evaluated the mean dominant frequency and relative power of EEG frequency bands.
resultsDogs with a normal pre-attenuation EEG (n = 24) did not develop early-onset (<7 days) PAS; however, 8% (2/24) experienced late-onset seizures (>30 days post-attenuation). Four dogs had abnormal pre-attenuation EEG. Two of these dogs developed early-onset seizures and 3 dogs (75%) died before discharge due to worsening neurological signs (n = 2) or immediate postoperative complication (n = 1). Pre-attenuation covert encephalopathy defined by EEG showed a combination of epileptiform features (4/4), abnormal background rhythm (3/4), and a lack of graphoelements of sleep (2/4). Median ammonia concentration (range) was 102.5 μg/dL (34-401) in non-encephalopathic dogs and 145.5 μg/dL (56-275) in dogs with covert encephalopathy. CONCLUSIONS AND CLINICAL IMPORTANCE: Electroencephalography could provide useful diagnostic biomarkers to identify dogs at high risk of developing neurological complications after attenuation of CPS. In this cohort, dogs with no abnormalities detected on preoperative EEG had favorable outcomes during their hospitalization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.