Evidence map›Paper›PMID 41742495›Full record

ArticleJournal of veterinary internal medicine2026

Owner points of view and perceived quality of life of diabetic cats pre- and post-hypophysectomy for hypersomatotropism.

Edward Shelton, Rosanne Jepson, David Church, Joe Fenn, Christopher Scudder

Erratum issuedAbstract read
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Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Edward SheltonDepartment of Clinical Science and Services, Royal Veterinary College, Hatfield AL9 7TA,  United Kingdom.
Rosanne JepsonDepartment of Clinical Science and Services, Royal Veterinary College, Hatfield AL9 7TA,  United Kingdom.
David ChurchDepartment of Clinical Science and Services, Royal Veterinary College, Hatfield AL9 7TA,  United Kingdom.
Joe FennDepartment of Clinical Science and Services, Royal Veterinary College, Hatfield AL9 7TA,  United Kingdom.
Christopher ScudderDepartment of Clinical Science and Services, Royal Veterinary College, Hatfield AL9 7TA,  United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypophysectomy provides the most favorable long-term outcome for cats with hypersomatotropism (HST) and concurrent diabetes mellitus (DM). HYPOTHESIS/

objectivesAssess owner perceptions of quality of life (QoL) of their diabetic cats pre- and post-hypophysectomy for HST. ANIMALS: Client-owned cats (27 retrospectively, 13 prospectively).

methodsOwners whose cats had undergone hypophysectomy between 2012 and 2022 for the management of HST with DM were identified. Owner telephone interviews were performed to formulate questions addressing points of view regarding HST and hypophysectomy. The DIAQoL-Pet questionnaire was adjusted to include newly formulated questions and distributed to owners. The questionnaire also was distributed to owners of cats with HST with DM pre-hypophysectomy (T0) and at least 3 months post-hypophysectomy (T1) between March 2023 and November 2024. Item-weighted impact score (IWIS) and an average-weighted impact score (AWIS) were calculated. The AWIS and IWIS at T0 and T1 for prospectively recruited cases were compared using the Wilcoxon signed rank test.

resultsNearly 92% (22 out of 24) of retrospective group respondents and 100% (10 out of 10) of prospective group respondents would definitely request hypophysectomy again. For paired prospective group responses, IWIS were significantly less negative postoperatively for "worry" (P = .02), "pet unwell" (P = .03), "worry hypoglycemia" (P = .01), and "worry vision" (P = .04). The median AWIS before (2.16; IQR, -4.23 to -1.17) and after (-1.27; IQR, -2.06 to -0.39) hypophysectomy were significantly less negative (P = .02). CONCLUSIONS AND CLINICAL IMPORTANCE: Most owners perceive hypophysectomy to be a beneficial intervention for their QoL and that of their cat.

Indexed as

acromegalydiabetic remissionfelinepituitarytranssphenoidal

Identifiers

PMID41742495
PMCPMC12881934

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.