Evidence map›Paper›PMID 41742266›Full record

ArticleVeterinary research2026

Vertical transmission of Orf virus in goats and its prevention.

Ming Pang, Furqan Munir, Jin Yao, Tianxing Wang, Shaofei Li, Yiming Chen, Ying Wen, Dekun Chen, Jun Liu, Wentao Ma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ming Pang *Key Laboratory of Animal Biotechnology of the Ministry of Agriculture of China, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling, 712100, Shaanxi, China.
Furqan Munir *Key Laboratory of Animal Biotechnology of the Ministry of Agriculture of China, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling, 712100, Shaanxi, China.
Jin YaoKey Laboratory of Animal Biotechnology of the Ministry of Agriculture of China, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling, 712100, Shaanxi, China.
Tianxing WangKey Laboratory of Animal Biotechnology of the Ministry of Agriculture of China, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling, 712100, Shaanxi, China.
Shaofei LiKey Laboratory of Animal Biotechnology of the Ministry of Agriculture of China, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling, 712100, Shaanxi, China.
Yiming ChenKey Laboratory of Animal Biotechnology of the Ministry of Agriculture of China, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling, 712100, Shaanxi, China.
Ying WenState Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, 810016, Qinghai, China.
Dekun ChenKey Laboratory of Animal Biotechnology of the Ministry of Agriculture of China, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling, 712100, Shaanxi, China.
Jun LiuKey Laboratory of Animal Biotechnology of the Ministry of Agriculture of China, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling, 712100, Shaanxi, China.
Wentao MaKey Laboratory of Animal Biotechnology of the Ministry of Agriculture of China, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling, 712100, Shaanxi, China. mawentao@nwafu.edu.cn.

Funding

Basic Research Program of Qinghai Province, China 2025-ZJ-952M
6 · The paper itself

Abstract

Contagious ecthyma dermatitis, caused by Orf virus (ORFV), is an important zoonotic disease of small ruminants, particularly goats and sheep, and can occasionally infect humans. The morbidity of the disease is high in newborn kids or lambs as compared with adult animals, even leading to death in severe cases due to emaciation or secondary infections. Despite its significance, the precise route of ORFV transmission to newborn kids or lambs has remained unclear. In this study, we hypothesized that ORFV may be transmitted transplacentally from dam to fetus and investigated the presence of the virus in maternal-fetal interface tissues. Molecular detection targeting the ORFV B2L gene provided evidence supporting vertical transmission. The average viral loads in placental cotyledons and umbilical cords were 10

Indexed as

Ecthyma, ContagiousGoat DiseasesInfectious Disease Transmission, VerticalOrf virusVaccinationViral VaccinesAnimalsFemaleGoatsPlacentaPregnancyViral Vaccinesgoatsinactivated vaccineOrf virusvertical transmission

Identifiers

PMID41742266
PMCPMC13041380

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.