ReviewMolecular biotechnology2026
Integrating Genetic and Biotechnological Approaches to Enhance High-CBD Cannabis sativa L. Cultivation for Medicinal Purposes.
Review in Molecular biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Genetic Advances inPlants (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing demand for cannabidiol (CBD) and the relaxation of legal restrictions have driven the rapid expansion of cannabis research, cultivation, and commercialization. This review synthesizes current knowledge on optimizing high-CBD cannabis cultivation, focusing on genetic, environmental, and technological determinants of yield, cannabinoid biosynthesis, and compliance with regulatory frameworks. Key aspects include genetic stabilization, molecular breeding, and CRISPR-based gene editing to ensure consistency in cannabinoid profiles; precision agronomy practices such as fertigation, irrigation, and controlled-environment agriculture; and the role of abiotic stresses, light spectrum, temperature, and photoperiod in modulating plant growth and secondary metabolism. Furthermore, the paper evaluates regulatory landscapes across regions, strain-specific performance, and the integration of artificial intelligence in trait selection and production monitoring. By linking molecular genetics with cultivation systems and global trade patterns, this review highlights pathways to enhance yield stability, product quality, and medicinal efficacy of high-CBD cannabis. The study highlights the pressing need for scientifically informed cultivation practices, harmonized regulatory standards, and interdisciplinary innovation to promote cannabis as a sustainable agricultural and medicinal resource.
Indexed as
Identifiers
41741936What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.