Evidence map›Paper›PMID 41741763›Full record

ArticleCommunications chemistry2026

Electrochemical Ferrier rearrangement of glycals in flow.

Pallav Suman, Mihhail Fokin, Kaarel Erik Hunt, Tõnis Kanger, Daniele Mazzarella, Maksim Ošeka

Abstract read
In one paragraph

Article in Communications chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pallav SumanDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618, Tallinn, Estonia.ORCID http://orcid.org/0009-0004-8571-5183
Mihhail FokinDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618, Tallinn, Estonia.ORCID http://orcid.org/0009-0000-6934-3309
Kaarel Erik HuntDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618, Tallinn, Estonia.ORCID http://orcid.org/0000-0003-3860-0194
Tõnis KangerDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618, Tallinn, Estonia.ORCID http://orcid.org/0000-0001-5339-9682
Daniele MazzarellaDepartment of Chemical Sciences and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica 1, 00133, Rome, Italy. daniele.mazzarella@uniroma2.it.ORCID http://orcid.org/0000-0001-7121-9796
Maksim OšekaDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618, Tallinn, Estonia. maksim.oseka@taltech.ee.ORCID http://orcid.org/0000-0002-7095-4497

Funding

Eesti Teadusagentuur (Estonian Research Council) PRG1031
6 · The paper itself

Abstract

The Ferrier rearrangement is a cornerstone transformation in carbohydrate chemistry, typically requiring strongly acidic or oxidative conditions. Here we report a continuous-flow electrochemical Ferrier rearrangement operating in an undivided microreactor equipped with inexpensive graphite electrodes mitigating batch process limitations, such as insufficient mass transfer and charge utilization. The process proceeds efficiently with minimal supporting electrolyte and charge input, converting a wide range of acyloxy- and alkoxyglycals with diverse oxygen-, sulfur-, nitrogen-, and carbon-based nucleophiles to 2,3-unsaturated glycosides in up to 94% yield and excellent diastereoselectivity. The short interelectrode distance enables completion under 20 seconds residence time, affording gram-scale productivity (10 mmol·h

Identifiers

PMID41741763
PMCPMC13046870

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.