ArticleNature2026
Peripheral immune-inducer dendritic cells drive early-life allergic inflammation.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- OX40 Ligand/OX40 Axis as the Inflammatory Prequel in Atopic Dermatitis: A Narrative Review.Dermatology and therapy · 2026Review
- Pediatric health: mechanistic insights into inflammatory diseases and emerging therapeutic pathway-targeted approaches.Translational pediatrics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Yue XingDepartment of Immunology and Immunotherapy, Precision Immunology Institute, Icahn School of Medicine at Mt Sinai, New York, NY, USA. Yue.Xing2@mssm.edu.ORCID http://orcid.org/0000-0001-5845-2286
Ilana ReznikovDepartment of Immunology and Immunotherapy, Precision Immunology Institute, Icahn School of Medicine at Mt Sinai, New York, NY, USA.
Abonti Nur AhmedDepartment of Immunology and Immunotherapy, Precision Immunology Institute, Icahn School of Medicine at Mt Sinai, New York, NY, USA.
Ikjot SidhuDepartment of Immunology and Immunotherapy, Precision Immunology Institute, Icahn School of Medicine at Mt Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-1470-6421
Jill WisnewskiDepartment of Biology, MIT, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-2976-3231
Asma FarhatDepartment of Immunology and Immunotherapy, Precision Immunology Institute, Icahn School of Medicine at Mt Sinai, New York, NY, USA.
Aleksandr PrystupaDepartment of Immunology and Immunotherapy, Precision Immunology Institute, Icahn School of Medicine at Mt Sinai, New York, NY, USA.
Piotr KoniecznyDepartment of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA.ORCID http://orcid.org/0000-0003-4114-349X
Kody MansfieldDepartment of Cell Biology, NYU Langone Health, New York, NY, USA.
Melissa L CooperNeuroscience Institute, NYU Medical Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-4337-8356
Stephen T YeungDivision of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-9710-5567
Madeline KimKimberly and Eric J Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sophia AdegheDepartment of Dermatology, Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA.
Katherine D GainesDepartment of Immunology and Immunotherapy, Precision Immunology Institute, Icahn School of Medicine at Mt Sinai, New York, NY, USA.ORCID http://orcid.org/0009-0005-8038-8870
Meredith MansonKimberly and Eric J Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ji Hyun SimInflammation and Autoimmunity Program, Hospital for Special Surgery Research Institute, New York, NY, USA.
Qingrong HuangCenter for Discovery & Innovation, Hackensack Meridian Health, Nutley, NJ, USA.ORCID http://orcid.org/0000-0002-7692-5160
Ata S MoshiriRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID http://orcid.org/0000-0001-6684-4503
Kamal M KhannaLaura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID http://orcid.org/0000-0002-9328-3817
Theresa T LuInflammation and Autoimmunity Program, Hospital for Special Surgery Research Institute, New York, NY, USA.ORCID http://orcid.org/0000-0002-5707-8744
Emma Guttman-YasskyKimberly and Eric J Waldman Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-9363-324X
Amanda W LundRonald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, NYU Langone Health, New York, NY, USA.ORCID http://orcid.org/0000-0001-7389-9983
Niroshana AnandasabapathyDepartment of Dermatology, Microbiology and Immunology, Weill Cornell Medicine, New York, NY, USA.
Shruti NaikDepartment of Immunology and Immunotherapy, Precision Immunology Institute, Icahn School of Medicine at Mt Sinai, New York, NY, USA. Shruti.Naik@mssm.edu.ORCID http://orcid.org/0000-0002-2216-5135
Funding
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MARK Reid PHILIPS · 1985 to 2026
$83.1MConduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4MVascular-stromal function and regulation in immunityR01AI079178 · NIAID · HOSPITAL FOR SPECIAL SURGERY · PI Theresa T. Lu · 2010 to 2026
$6.6MInterrogating unique DC adaptations to tissue to promote barrier immunity and toleranceR01AR080436 · NIAMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Niroshana Anandasabapathy · 2022 to 2026
$3.5MNovel lung resident interstitial macrophage subset with distinct localization and polarizationR01AI143861 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KHANNA, KAMAL MOHAN · 2019 to 2023
$3.3MMechanisms of immune-epithelial crosstalk in tissue repairR01AI168462 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Shruti Naik · 2022 to 2026
$3.1MLangerhans cells and lymphatic regulation in immunityR01AR084694 · NIAMS · HOSPITAL FOR SPECIAL SURGERY · PI Theresa T. Lu · 2024 to 2026
$2.2MNew mechanisms governing skin tissue residency memory T cellsR01AR083208 · NIAMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Niroshana Anandasabapathy · 2024 to 2026
$2.1MUncovering Novel Microbial Factors That Enhance Wound RepairR01AR086237 · NIAMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI NAIK, SHRUTI · 2025 to 2025
$2.1MCOVID and Translational Science supercomputer (CATS)S10OD030463 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2021 to 2021
$2.0MBig Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0MDecoding mechanisms of early life inflammationR01AI184905 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Shruti Naik · 2025 to 2026
$1.6MNCATS NIH HHS UL1 TR004419NCI NIH HHS P30 CA016087NIAID NIH HHS R01 AI079178NIAID NIH HHS R01 AI143861NIAID NIH HHS R01 AI168462NIAID NIH HHS R01 AI184905NIAMS NIH HHS K99 AR083536NIAMS NIH HHS R00 AR083536NIAMS NIH HHS R01 AR080436NIAMS NIH HHS R01 AR083208NIAMS NIH HHS R01 AR084694NIAMS NIH HHS R01 AR086237NIH HHS S10 OD026880NIH HHS S10 OD030463
Abstract
Atopic diseases associated with allergens, as well as allergic diseases, frequently arise early in life; however, the age-dependent mechanisms governing immune responses to allergens remain poorly understood
Indexed as
Dendritic CellsHypersensitivityInflammationAllergensAnimalsDermatitis, AtopicFemaleInterleukin-23LungLymph NodesMaleMiceMice, Inbred C57BLReceptors, Antigen, T-Cell, gamma-deltaSkinTh17 CellsAllergensInterleukin-23Receptors, Antigen, T-Cell, gamma-delta
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.