Evidence map›Paper›PMID 41741642›Full record

ArticleNature2026

CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis.

Lingzhi Wu, Jianqin Wang, Yawei Wang, Junhan Yang, Yuanhang Yao, Yonglun Wang, Dong Huang, Yating Hu, Xinxuan Xu, Renqian Wang and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Lingzhi Wu *State Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Jianqin Wang *Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.ORCID 0000-0001-9098-3837
Yawei Wang *PKU-THU Joint Center for Life Sciences, Peking University, Beijing, China.
Junhan YangState Key Laboratory of Membrane Biology, Peking-Tsinghua Joint Center for Life Sciences, Scholar of Life Sciences, Peking University, Beijing, China.ORCID 0009-0005-7654-7744
Yuanhang YaoState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Yonglun WangState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Dong HuangState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Yating HuState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Xinxuan XuState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Renqian WangState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Wenjing DuState Key Laboratory of Membrane Biology, Peking-Tsinghua Joint Center for Life Sciences, Scholar of Life Sciences, Peking University, Beijing, China.
Yiting ShiState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Quan LiState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Lu LiuState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Yuangang ZhuState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Shijie LiShanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China.
Feng-Jung ChenShanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-0041-003X
Xiuqin ZhangState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.
Xiao WangState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China.ORCID 0009-0001-1797-1239
Qiang GuoState Key Laboratory of Membrane Biology, Peking-Tsinghua Joint Center for Life Sciences, Scholar of Life Sciences, Peking University, Beijing, China. guo.qiang@pku.edu.cn.ORCID 0000-0003-3520-5439
Li XuTsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China. xulilulu@tsinghua.edu.cn.ORCID 0000-0002-0927-9357
Peng LiTsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China. li-peng@mail.tsinghua.edu.cn.ORCID 0000-0002-8629-5246
Xiao-Wei ChenState Key Laboratory of Membrane Biology and Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing, China. xiaowei_chen@pku.edu.cn.ORCID 0000-0001-6466-6248

Funding

Beijing Outstanding Young Scientist ProgramNational Key R&D ProgramNational Science Foundation of China
6 · The paper itself

Abstract

Orchestration of lipid production, storage and mobilization is vital for cellular and systemic homeostasis

Indexed as

Endoplasmic ReticulumLipid BilayersLipid MetabolismAnimalsApolipoproteins BFatty LiverFemaleHomeostasisHumansLipid DropletsLiverMaleMicePhospholipidsPhospholipid Transfer ProteinsApolipoproteins BLipid BilayersPhospholipidsPhospholipid Transfer Proteins

Identifiers

PMID41741642
PMCPMC13061606

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.