Evidence map›Paper›PMID 41741604›Full record

ArticleScientific reports2026

Medication adherence barriers and digital support among Saudi adults with chronic conditions.

Mohammed M Aldurdunji, Ohood K Almuzaini, Abdulelah A Alfattani, Abdulrahman I Almaghrabi, Ahmad E Alqurashy, Khaled T Alharbi, Saeed H Alzahrani, Moayed M Kenkar, Mutep H Aljahdali, Saad M Wali

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohammed M AldurdunjiPharmaceutical Practices Department, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia. mmdurdunji@uqu.edu.sa.
Ohood K AlmuzainiPharmacology and Toxicology Department, College of Pharmacy, Umm Al- Qura University, Makkah, Saudi Arabia.
Abdulelah A AlfattaniPharmaceutical Sciences Department, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Abdulrahman I AlmaghrabiCollege of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Ahmad E AlqurashyCollege of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Khaled T AlharbiCollege of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Saeed H AlzahraniCollege of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Moayed M KenkarCollege of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Mutep H AljahdaliCollege of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Saad M WaliPharmacology and Toxicology Department, College of Pharmacy, Umm Al- Qura University, Makkah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medication adherence is essential for managing chronic diseases, yet non-adherence remains a significant public health issue globally and regionally. In Saudi Arabia, behavioral and systemic barriers to adherence are understudied, particularly regarding the role of digital tools. To evaluate the knowledge, attitudes, and practices related to medication adherence among adults with chronic conditions in Saudi Arabia and to identify barriers and facilitators influencing adherence, including digital support tools. A cross-sectional survey was conducted in Q1 2025 across multiple regions in Saudi Arabia. Adults with chronic illnesses were recruited using convenience sampling. A validated electronic questionnaire assessed knowledge, attitudes, intentional non-adherence, and digital tool use. Data were analyzed using descriptive statistics and multivariate logistic regression to identify predictors of non-adherence. A total of 950 participants were included (mean age: 48.6 years; 73.9% female). Although 65.9% strongly agreed on the importance of medication, 30.0% reported intentional non-adherence. Middle-aged adults (50–59 years) and males were more likely to alter or skip medications. Forgetfulness and dislike of medications were the most reported reasons. Only 24.2% used digital tools, primarily for reminders. Gender differences were observed in adherence strategies, with women more likely to use organizers and men relying on family or mobile apps. Positive beliefs about medication necessity were significantly associated with higher adherence and digital tool engagement. Medication adherence remains suboptimal among adults with chronic conditions in Saudi Arabia, influenced by demographic, behavioral, and technological factors. Tailored interventions addressing gender-specific needs, behavioral motivations, and digital literacy are warranted to improve long-term adherence and disease outcomes.

Indexed as

Drug MonitoringMedication AdherenceAdherence InterventionsAdultAgedChronic DiseaseCross-Sectional StudiesDigital HealthFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedSaudi ArabiaSurveys and QuestionnairesChronic diseaseDigital healthMedication adherencePatient behaviorSaudi Arabia

Identifiers

PMID41741604
PMCPMC12979819

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.