Evidence map›Paper›PMID 41741515›Full record

ArticleScientific reports2026

Novel eugenol/limonene nanoplatform as a new remedy against bacterial lung infections.

Bassma H Elwakil, Marwa M Shaaban, Basant A Bakr, Moaaz T Hamed, Keshav Raj Paudel, Adel M Atia, Mohamed Zakaria

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bassma H ElwakilMedical Laboratory Technology Program, Faculty of Applied Health Sciences Technology, Galala University, Suez, Egypt. basmahasan35@yahoo.com.
Marwa M ShaabanDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21568, Egypt.
Basant A BakrFaculty of Physical Therapy, Pharos University in Alexandria, Canal El Mahmoudia Street, Beside Green Plaza Complex, Alexandria, 21648, Egypt.
Moaaz T HamedDepartment of Botany & Microbiology, Faculty of Science, Alexandria University, Alexandria, 21568, Egypt.
Keshav Raj PaudelCentre for Inflammation, School of Life Sciences, Faculty of Science, Centenary Institute and University of Technology Sydney, Sydney, NSW, 2007, Australia.
Adel M AtiaDepartment of Chemistry, Faculty of Science, Alexandria University, Alexandria, 21568, Egypt.
Mohamed ZakariaDepartment of Chemistry, Faculty of Science, Alexandria University, Alexandria, 21568, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A combinational approach to antimicrobial design emerges from a nanoemulsified nanoplatform from the union of two Egyptian essential oils-orange peel and clove-whose distinct chemistries were revealed by GC-MS. Orange EO is dominated by D-limonene (63.25%), with supporting alkyl-benzenes (22.92%) and β-myrcene (1.41%), while clove EO centers on Eugenol (36.20%), Caryophyllene (19.30%), Eugenol acetate (18.71%), along with alkyl-benzenes (11.86%) and humulene (2.41%). The chemical consonance between Eugenol and Limonene hints at a cooperative assembly: their lipophilic profiles enable the formation of nanoemulsified nanoparticles from their emulsion blend, potentially amplifying bioavailability and multi-target action. Biologically, Eugenol/Limonene demonstrates tangible antimicrobial activity. In a direct DHFR inhibition assay, the nanoformulation inhibits DHFR with an IC

Indexed as

Anti-Bacterial AgentsEugenolLimoneneNanoparticlesAnimalsMicrobial Sensitivity TestsOils, VolatileAnti-Bacterial AgentsEugenolLimoneneOils, VolatileNanoplatformNatural oilsPneumonia model

Identifiers

PMID41741515
PMCPMC12949021

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.