Evidence map›Paper›PMID 41741215›Full record

ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2026

The Anterior Cingulate Cortex and Prosocial Behavior toward Others in Negative State.

Mingmin Zhang, Nicole Rigney, Steve W C Chang, Weizhe Hong

Abstract readReview
In one paragraph

Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Central Questions for Social Neuroscience Research.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mingmin ZhangDepartments of Neurobiology and Biological Chemistry, University of California, Los Angeles, California 90095.
Nicole RigneyDepartments of Neurobiology and Biological Chemistry, University of California, Los Angeles, California 90095.
Steve W C ChangDepartments of Psychology and Neuroscience, Kavli Institute for Neuroscience, and Wu Tsai Institute, Yale University, New Haven, Connecticut 06510.ORCID 0000-0003-4160-7549
Weizhe HongDepartments of Neurobiology and Biological Chemistry, University of California, Los Angeles, California 90095 whong@ucla.edu.ORCID 0000-0003-1523-8575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prosocial behaviors, voluntary actions benefiting others, are essential for social bonds and group survival across species from insects to primates. This review examines the neurobiological foundations of prosocial behavior, with an emphasis on the role of the cingulate cortex (particularly the anterior cingulate cortex), in mediating prosocial and helping actions toward others in distress. We summarize recent studies across species and discuss how different parts of the cingulate cortex process information about others' behavioral states, encode empathetic responses, and regulate prosocial actions. Critical gaps remain in establishing causal links between perceiving others' needs, experiencing empathetic responses, and executing helping behaviors. Addressing these challenges requires novel experimental designs capable of independently manipulating these interrelated processes.

Indexed as

EmpathyGyrus CinguliSocial BehaviorAnimalsHelping BehaviorHumansanterior cingulate cortexempathyhelpingprosocial behavior

Identifiers

PMID41741215
PMCPMC12940452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.