ArticleJournal of applied clinical medical physics2026
Quantitative evaluation of a deep learning-based noise reduction algorithm in digital radiography using noise power spectrum analysis.
Article in Journal of applied clinical medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Noise characteristics in synthetic mammography derived from digital breast tomosynthesis: a comparison with conventional digital mammography.Radiological physics and technology · 2026Article
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2 authors.
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Abstract
backgroundRecently, deep learning (DL)-based noise reduction (DLNR) has been introduced in clinically used digital radiography (DR) systems, reporting superior performance over conventional algorithms. However, DLNR algorithms often operate as "black boxes" with nonlinear behavior, making it essential to understand the impact of such processing on image quality under different imaging conditions. PURPOSE: This study aimed to quantitatively evaluate the image quality of a commercial DLNR algorithm for DR referred to as intelligent noise reduction (INR). Specifically, we compared its noise reduction performance with that of a conventional rule-based algorithm (conventional noise reduction, Con-NR) using frequency-domain metrics with detailed noise power spectrum (NPS) analysis.
methodsThe NPS was used to assess the spatial-frequency-dependent behavior of both INR and Con-NR across varying dose levels and different objects. In this work, we introduced a supplementary metric-the NPS improvement factor (NPSIF)-to quantify noise suppression across frequency ranges and facilitate direct comparison between methods.
resultsThe DL-based algorithm achieved substantial noise reduction at low-dose settings compared with the conventional method, although its advantages were less pronounced at higher dose levels. The NPSIF effectively captured frequency-specific differences, thereby offering insights into the strengths and limitations of each technique.
conclusionsThe dose-dependent performance of the DL-based algorithm suggests sensitivity to the characteristics of the training data used to develop the DL model. The findings demonstrate distinct differences in the noise suppression behavior between DL-based and conventional methods in DR and underscore the importance of detailed frequency-domain evaluation for understanding advanced image processing. Further research is warranted to integrate noise analysis with diagnostic performance metrics to comprehensively assess clinical utility.
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