Evidence map›Paper›PMID 41741020›Full record

ReviewInternational wound journal2026

A Systematic Review of the Cost-Effectiveness of Interventions for Chronic Wounds.

Petra Marešová, Kristina Randlová, Lukáš Režný, Jan Hruška, Barbara Wolff-Winiski, Damien Dupin, Kamil Kuča

Abstract readReview
In one paragraph

Review in International wound journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Petra MarešováBetthera s.r.o, Hradec Kralove, Czech Republic.ORCID https://orcid.org/0000-0002-1218-501X
Kristina RandlováBetthera s.r.o, Hradec Kralove, Czech Republic.ORCID https://orcid.org/0009-0004-0139-1020
Lukáš RežnýBetthera s.r.o, Hradec Kralove, Czech Republic.ORCID https://orcid.org/0000-0001-6584-6742
Jan HruškaBetthera s.r.o, Hradec Kralove, Czech Republic.ORCID https://orcid.org/0000-0001-7429-5524
Barbara Wolff-WiniskiAkribes Biomedical GmbH, Vienna, Austria.ORCID https://orcid.org/0000-0002-5567-581X
Damien DupinCIDETEC, Basque Research and Technology Alliance (BRTA), Parque Científico y Tecnológico de Gipuzkoa, Donostia-San Sebastián, Spain.ORCID https://orcid.org/0000-0003-0868-9028
Kamil KučaBetthera s.r.o, Hradec Kralove, Czech Republic.ORCID https://orcid.org/0000-0001-9664-1109

Funding

HORIZON-CL4-2022-RESILIENCE-01-13 101092243
6 · The paper itself

Abstract

Chronic wounds present a significant challenge to society and have a negative impact on the quality of life and daily activities of patients. This review aimed to identify the cost-effectiveness of the currently used care alternatives for the treatment of chronic wounds. This study serves to identify cost-effectiveness boundaries and provide a basis for determining the cost-effectiveness of the proposed care alternatives. A systematic literature search was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Articles published on Web of Science and PubMed from June 2013 to June 2023 were included. A comparative analysis was performed using the data adjusted for inflation and transformed for the same time horizon. The median time to heal was approximately 2.5 months in the first quartile of studies ending at 1.3 months and the third quartile ending at 3.7 months. The average cost of complete chronic wound healing for all care alternatives in the study sample was $6435, with a median cost of $5814. This systematic review covers a diverse range of treatment alternatives, their health effects and costs and highlights the complex landscape of cost-effectiveness in the treatment of chronic wounds. Trial Registration: PROSPERO database under registration number: CRD42023434074.

Indexed as

arterial ulcerschronic wound healingchronic woundscost‐effectivenessdiabetic foot ulcersvenous ulcers

Identifiers

PMID41741020
PMCPMC12935516

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.