ArticleBMJ open ophthalmology2026
Is metamorphopsia more important than visual acuity in vitreomacular interface disorders? A scoping review.
Article in BMJ open ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
backgroundVitreomacular interface disorders are known to reduce vision-related quality of life (VR-QoL). This is due to both reduced visual acuity and metamorphopsia. In clinical practice, visual acuity is measured routinely, but quantitative measurements of metamorphopsia are less frequent. We conducted a scoping literature review to determine whether metamorphopsia or visual acuity has the greatest effect on VR-QoL.
methodsA literature review, of studies published in English, and indexed in Medline or Embase, in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. 65 studies were identified. 55 were excluded as they did not meet the inclusion criteria.
resultsOf the 10 publications, six studied epiretinal membrane, two studied full-thickness macular hole, one studied vitreomacular traction with or without macular hole and one included both macular hole and epiretinal membrane. A variety of different methods were used to measure metamorphopsia and VR-QoL. Of the eight studies reporting the association between preoperative metamorphopsia and VR-QoL, five found a significant correlation. Six studies examined the association between post-operative metamorphopsia and VR-QoL, five of which found a significant correlation. Five studies looked for any link between reduction in metamorphopsia and improvement in VR-QoL. All five found a significant association. In contrast, only two of eight studies found any association between preoperative vision and VR-QoL, and none found any relationship between improvement in visual acuity and improvement in VR-QoL.
conclusionsAlthough the published evidence is limited, it appears that metamorphopsia may be a better predictor of preoperative and postoperative VR-QoL than visual acuity. Further research is necessary to confirm this, but metamorphopsia should be measured when assessing vitreomacular interface disorders.
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