ArticleAmerican journal of physiology. Cell physiology2026
Characterization of cardiac disease-associated mutations in RyR2 Ca
Venkat R Chirasani, Akanksha Patwardhan, Naohiro Yamaguchi
Abstract read
In one paragraphArticle in American journal of physiology. Cell physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
3 authors.
Venkat R ChirasaniDepartment Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States.ORCID 0000-0003-1416-0438 Akanksha PatwardhanDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, South Carolina, United States.
Naohiro YamaguchiDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, South Carolina, United States.ORCID 0000-0001-5933-1507 Funding
Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5MSouth Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1MFunctional implications of CPVT1-associated RyR2 mutations in human cardiomyocytesR01HL153504 · NHLBI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI MORAD, MARTIN, YAMAGUCHI, NAOHIRO · 2021 to 2024
$2.0MHHS | National Institutes of Health (NIH) R01HL153504MUSC | South Carolina Clinical and Translational Research Institute, Medical University of South Carolina (SCTR) UL1TR001450NCATS NIH HHS UL1 TR001450NCI NIH HHS P30 CA016086NHLBI NIH HHS R01 HL153504UNC | UNC | Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill (UNC Lineberger) P30CA016086
6 · The paper itselfAbstract
Indexed as
CaffeineCalciumHeart DiseasesMutationRyanodine Receptor Calcium Release ChannelAnimalsBinding SitesCalcium SignalingHEK293 CellsHumansMolecular Dynamics SimulationMutation, MissenseProtein BindingCaffeineCalciumRyanodine Receptor Calcium Release ChannelRyR2 protein, humanCa2+-dependent regulationcardiac diseaseryanodine receptorsarcoplasmic reticulumstructural modeling
Identifiers
PMID41740622
PMCPMC13048304
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