Moderated Effects of Latinx Ethnicity for a Stepped-Care, Technology and Counseling-Based Intervention (Positive STEPS) on Antiretroviral Adherence and Viral Load Suppression Among Youths With HIV, United States, 2018‒2023.

Elizabeth A Yonko, Robert Garofalo, Matthew J Mimiaga

Registry-linked trialAbstract readRandomized Controlled Trial

In one paragraph

Trial report in American journal of public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03092531 (Adaptive Intervention Strategies Trial for Strengthening Adherence to Antiretroviral HIV Treatment Among Youth), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03092531 nacompletednot on this map

Adaptive Intervention Strategies Trial for Strengthening Adherence to Antiretroviral HIV Treatment Among Youth

TypeinterventionalSponsorUniversity of California, Los AngelesRan2018 to 2024Enrolled123ConditionsAdherenceArmsPositive STEPS

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth A YonkoElizabeth A. Yonko and Matthew J. Mimiaga were with the Department of Epidemiology at UCLA Fielding School of Public Health, and UCLA's Center for LGBTQ+ Advocacy, Research and Health (C-LARAH), Los Angeles, CA, at the time of this study. M. J. Mimiaga was additionally with the Department of Psychiatry and Biobehavioral Sciences at UCLA David Geffen School of Medicine, Los Angeles, and The Fenway Institute at Fenway Health, Boston, MA. Robert Garofalo was with the Potocsnak Family Division of Adolescent and Young Adult Medicine at the Ann & Robert H. Lurie Children's Hospital, and the Department of Pediatrics at Northwestern University Feinberg School of Medicine, Chicago, IL.ORCID 0000-0003-4065-1820

Robert GarofaloElizabeth A. Yonko and Matthew J. Mimiaga were with the Department of Epidemiology at UCLA Fielding School of Public Health, and UCLA's Center for LGBTQ+ Advocacy, Research and Health (C-LARAH), Los Angeles, CA, at the time of this study. M. J. Mimiaga was additionally with the Department of Psychiatry and Biobehavioral Sciences at UCLA David Geffen School of Medicine, Los Angeles, and The Fenway Institute at Fenway Health, Boston, MA. Robert Garofalo was with the Potocsnak Family Division of Adolescent and Young Adult Medicine at the Ann & Robert H. Lurie Children's Hospital, and the Department of Pediatrics at Northwestern University Feinberg School of Medicine, Chicago, IL.ORCID 0000-0001-9513-9416

Matthew J MimiagaElizabeth A. Yonko and Matthew J. Mimiaga were with the Department of Epidemiology at UCLA Fielding School of Public Health, and UCLA's Center for LGBTQ+ Advocacy, Research and Health (C-LARAH), Los Angeles, CA, at the time of this study. M. J. Mimiaga was additionally with the Department of Psychiatry and Biobehavioral Sciences at UCLA David Geffen School of Medicine, Los Angeles, and The Fenway Institute at Fenway Health, Boston, MA. Robert Garofalo was with the Potocsnak Family Division of Adolescent and Young Adult Medicine at the Ann & Robert H. Lurie Children's Hospital, and the Department of Pediatrics at Northwestern University Feinberg School of Medicine, Chicago, IL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report findings from a secondary analysis examining moderated effects by Latinx ethnicity of an efficacious, stepped-care, technology and counseling-based intervention-Positive Strategies to Enhance Problem-Solving Skills (Positive STEPS)-to improve antiretroviral adherence and viral load suppression among adolescents and young adults with HIV in the United States. Latinx participants randomized to the Positive STEPS arm, relative to a standard-of-care control, experienced equal or greater improvements in antiretroviral adherence and viral load suppression compared with their non-Latinx peers. These findings suggest that Positive STEPS addresses unique behavioral and psychosocial barriers to HIV treatment adherence and viral load suppression among Latinx adolescents and young adults. ClinicalTrials.gov identifier: NCT03092531

Indexed as

Anti-HIV AgentsCounselingHispanic or LatinoHIV InfectionsMedication AdherenceViral LoadAdherence InterventionsAdolescentFemaleHumansMaleUnited StatesYoung AdultAnti-HIV Agents

Identifiers

PMID41740073

DOI10.2105/AJPH.2025.308341

PMCPMC12937184

What OpenQuestion holds

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Registered trials

NCT03092531ClinicalTrials.gov

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.