Evidence map›Paper›PMID 41739933›Full record

ArticleScience advances2026

Planar cell polarity emerges through polarized accumulation of Wnt11.

Yusuke Mii, Minako Suzuki, Hiroshi Koyama, Kei Nakayama, Ritsuko Takada, Tomoe Kobayashi, Motosuke Tsutsumi, Tomomi Nemoto, Makoto Matsuyama, Toshihiko Fujimori and 1 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yusuke MiiNational Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan.ORCID 0000-0002-1907-5665
Minako SuzukiNational Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan.ORCID 0000-0002-2465-0206
Hiroshi KoyamaNational Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan.ORCID 0000-0002-1217-6754
Kei NakayamaNational Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan.ORCID 0000-0001-8032-7940
Ritsuko TakadaNational Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan.ORCID 0000-0002-1615-056X
Tomoe KobayashiShigei Medical Research Institutes, 2117 Yamada, Minami-ku, Okayama 701-0202, Japan.
Motosuke TsutsumiExploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan.ORCID 0000-0002-5832-3828
Tomomi NemotoExploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan.ORCID 0000-0001-6102-1495
Makoto MatsuyamaShigei Medical Research Institutes, 2117 Yamada, Minami-ku, Okayama 701-0202, Japan.ORCID 0000-0003-2606-059X
Toshihiko FujimoriNational Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan.ORCID 0000-0001-5200-4634
Shinji TakadaNational Institute for Basic Biology, National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi 444-8787, Japan.ORCID 0000-0003-4125-6056

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Planar cell polarity (PCP) is established by asymmetric localization of core PCP components in each cell. Because some Wnt proteins can induce PCP in vertebrates, it has been proposed that Wnt concentration gradients provide spatial cues for polarization. However, here, we present evidence that Wnt11 can regulate PCP in a gradient-independent manner. In the neural plate of

Identifiers

PMID41739933
PMCPMC12935041

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.