ArticleScience advances2026
The thermodynamic opportunities hypothesis: Metabolic temperature insensitivity across flatfish species.
Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
This study challenges widely held metabolic theory, which suggests that whole-animal metabolic rates increase with temperature because of its universal effects on the kinetics of the underlying biochemical reactions. Here, we show that metabolic rates across flatfish species are largely invariant from poles to the equator, which points to an explanation for interspecific thermal sensitivity based on ecology and evolution rather than thermodynamic constraints. The explanation proposed here is that warm water provides a thermodynamic opportunity, not a mandate, for metabolic rate escalation when required for predator-prey interactions. Flatfish do not require metabolic escalation because of their reliance on camouflage that mitigates the greater predation intensity in tropical waters. These findings have strong implications for models attempting to diagnose the response of organisms to climate change and for macroecological patterns more generally.
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Registered trials
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