ArticlePloS one2026
Controlled deposition of human neural stem cells on fiber substrates using gel encapsulation.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electrospinning is a versatile technique for manufacturing micro-nano diameter fibers and has been used extensively for tissue engineering in vivo and advanced cell culture in vitro. Standard means of seeding cells onto such substrates typically offer no control over cell distribution, yielding dispersed, heterogeneous and low concentrations of cells. In this article, we investigate the viability of using a simple bioprinting-inspired device for seeding gel-encapsulated cells onto fiber substrates. Using human neural stem cells, we were able to consistently seed cells with spatial control. We examined their long-term development, showing viable cells and normal differentiation potential. Furthermore, this device was able to seed on multiple sites within a single substrate, creating isolated populations and demonstrating the potential for this approach as a low-cost alternative to bioprinting systems, which is also applicable to somewhat challenging 3D substrates like electrospun fibers.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.