ArticleChemistry & biodiversity2026
Linking Metabolomic Diversity to Pharmacological Potency in Anonidium mannii Leaf Extracts.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Medicinal plants remain vital to drug discovery due to their diverse secondary metabolites. Anonidium mannii, an underutilized plant traditionally used for fever, diabetes, cancers, and infections, was evaluated for its pharmacological and metabolomic profiles using hexane, chloroform, and butanol-water extracts. Antibacterial activity against six pathogenic bacteria, antioxidant potential (2,2-diphenyl-1-picrylhydrazyl (DPPH) assay), and cytotoxicity on Vero and HepG2 cells (MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay) were assessed. Chemical profiling employed integrated LC-MS and GC-MS. The butanol-water extract exhibited strong antibacterial effects (MIC: 0.62-5.0 mg/mL) and potent antioxidant activity (IC
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