Proton transfer reagent cations for ion-ion charge state manipulation of high mass negatively-charged analytes in an electrodynamic ion trap.

Nicholas R Ellin, Boukar K S Faye, Seth A Horn, Alexander M Koers, Scott A McLuckey

Abstract read

In one paragraph

Article in The Analyst, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicholas R EllinDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA. mcluckey@purdue.edu.ORCID http://orcid.org/0009-0009-1415-5779

Boukar K S FayeDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA. mcluckey@purdue.edu.ORCID http://orcid.org/0009-0002-8928-6879

Seth A HornDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA. mcluckey@purdue.edu.ORCID http://orcid.org/0000-0003-2553-2794

Alexander M KoersDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA. mcluckey@purdue.edu.ORCID http://orcid.org/0009-0000-6255-1973

Scott A McLuckeyDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907-2084, USA. mcluckey@purdue.edu.ORCID http://orcid.org/0000-0002-1648-5570

Funding

Novel Ion Chemistry and Instrument Development for the Characterization of Proteins, Nucleic Acids, and Heterogeneous Bio-complexes via Tandem Mass SpectrometryR35GM153191 · NIGMS · PURDUE UNIVERSITY · PI SCOTT A MCLUCKEY · 2024 to 2026

$1.1M

NIGMS NIH HHS R35 GM153191

6 · The paper itself

Abstract

This work summarizes the criteria for a useful reagent for ion/ion proton transfer in an electrodynamic ion trap with specific emphasis on proton transfer to high mass multiply-charged analyte ions. A readily available and ionizable weak base of relatively high mass meets the criteria. The protonated form of an extensively fluorinated 10-carbon primary amine (1

Identifiers

PMID41739648

DOI10.1039/d5an01354b

PMCPMC12935111

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.