Evidence map›Paper›PMID 41739568›Full record

ArticleEmerging microbes & infections2026

TOR3A represses type I interferon production and limits viral clearance during respiratory syncytial virus infection.

Xiaoping Li, Zhengrong Chen, Mengyun Wu, Peijie Zhu, Guodong Qiao, Jiaoyang Li, Yunfei Ye, Jiamin Cai, Ying Zhou, Xiaoqiu Dai and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Xiaoping LiThe First Affiliated Hospital, Institutes of Biology and Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, People's Republic of China.ORCID 0000-0001-7932-6449
Zhengrong ChenDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, People's Republic of China.
Mengyun WuInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Peijie ZhuInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Guodong QiaoInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Jiaoyang LiDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, People's Republic of China.
Yunfei YeInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Jiamin CaiInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Ying ZhouInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Xiaoqiu DaiInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Yufeng WangDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, People's Republic of China.
Cancheng LiInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Jiaqi HuangDepartment of Respiratory Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Ji ZhouInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Fei XuInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Chensheng TanInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Yu ShaoInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Xiu GaoInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Jingjing HuInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Xuena XuDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, People's Republic of China.
Chunsheng DongInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.
Chuangli HaoDepartment of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, People's Republic of China.
Yi YangInstitutes of Biology and Medical Sciences, Suzhou University, Suzhou, People's Republic of China.ORCID 0000-0003-1620-1125
Jinping ZhangThe First Affiliated Hospital, Institutes of Biology and Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, People's Republic of China.ORCID 0000-0001-5537-5131

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type I interferons (IFN-I) are essential for antiviral immunity, and precise regulation of IFN-I production is crucial to balance viral clearance and immunopathology. Here, we demonstrate that the interferon-stimulated gene

Indexed as

Interferon Type IRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAnimalsDEAD Box Protein 58HumansImmune EvasionMacrophagesReceptors, ImmunologicSignal TransductionSTAT1 Transcription FactorUbiquitinationUbiquitin-Protein LigasesViral LoadDEAD Box Protein 58Interferon Type IReceptors, ImmunologicRIGI protein, humanSTAT1 protein, humanSTAT1 Transcription FactorUbiquitin-Protein LigasesmacrophagesRIG-IRSVTOR3Aubiquitination

Identifiers

PMID41739568
PMCPMC12990277

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.