Evidence map›Paper›PMID 41739555›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Programmed meiotic errors facilitate dichotomous sperm production in the silkworm,

Leif Benner, Makenzie Richmond, Youbin Xiang, LingSze Lee, Clio B Hockens, Tianwei Li, Zulin Yu, Dai Tsuchiya, Shengping Huang, Eelco C Tromer and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Leif Benner *Unit on Chromosome Dynamics, Division of Development Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20982.
Makenzie Richmond *Stowers Institute for Medical Research, Kansas City, MO 64110.ORCID 0009-0006-4500-2570
Youbin Xiang *Stowers Institute for Medical Research, Kansas City, MO 64110.
LingSze Lee *Unit on Chromosome Dynamics, Division of Development Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20982.ORCID 0000-0002-7129-9500
Clio B HockensUnit on Chromosome Dynamics, Division of Development Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20982.
Tianwei LiMolecular Genomics Core, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20982.
Zulin YuStowers Institute for Medical Research, Kansas City, MO 64110.ORCID 0000-0002-1292-8426
Dai TsuchiyaStowers Institute for Medical Research, Kansas City, MO 64110.ORCID 0000-0001-8385-2775
Shengping HuangStowers Institute for Medical Research, Kansas City, MO 64110.
Eelco C TromerCell Biochemistry, Groningen Biomolecular Sciences & Biotechnology Institute, Faculty of Science and Engineering, University of Groningen, Linneausborg, Groningen 9747 AG, the Netherlands.ORCID 0000-0003-3540-7727
R Scott HawleyStowers Institute for Medical Research, Kansas City, MO 64110.
Leah F RosinUnit on Chromosome Dynamics, Division of Development Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20982.ORCID 0000-0002-2489-4016

Funding

Investigating chromosome structure and function across species using Oligopaints and genomicsZIAHD009019 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ROSIN, LEAH · 2024 to 2025
$3.7M
HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) HD009019-01Intramural NIH HHS ZIA HD009019Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO) VI.Veni.202.223Stowers Institute for Medical Research (SIMR) N/A
6 · The paper itself

Abstract

The goal of meiosis is typically to produce haploid gametes (eggs or sperm). Failure to do so is catastrophic for fertility. However, Lepidopteran (moths and butterflies) males produce two sperm morphs: nucleated (eupyrene) sperm and anucleated (apyrene) sperm, both of which are essential for fertilization. The meiotic differences in the two types of spermatogenesis are unclear, and our knowledge of the molecular differences between eupyrene and apyrene spermatogenesis is extremely limited in all systems. The only factor identified as being required for apyrene spermatogenesis is

Indexed as

BombyxMeiosisSpermatogenesisSpermatozoaAnimalsInsect ProteinsMaleSpermatocytesInsect Proteinsapyreneeupyreneholocentricmeiosisspermatogenesis

Identifiers

PMID41739555
PMCPMC12956816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.