ReviewAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2026
Advanced electrochemical biosensing exploiting mussel-inspired polydopamine interfaces.
Review in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review comprehensively examines the burgeoning field of electrochemical biosensors enhanced by mussel-inspired polydopamine (PDA) interfaces. PDA, derived from the oxidative self-polymerization of dopamine, offers remarkable substrate-independent adhesion, versatile chemical reactivity via catechol and amine groups, and inherent biocompatibility, making it an attractive material for surface functionalization in biosensing. We delve into the fundamental aspects of PDA synthesis pathways and the resulting physicochemical properties crucial for electrode modification, including adhesion mechanisms, film formation control, functional group availability, and electrochemical characteristics. Diverse strategies for engineering PDA interfaces on electrode surfaces are systematically reviewed, encompassing direct coating, composite formation with various nanomaterials such as graphene, carbon nanotubes, and metal/metal oxide nanoparticles, layer-by-layer assembly, and controlled electropolymerization. The review categorizes and critically analyzes the wide array of applications reported for PDA-based electrochemical biosensors, focusing on the detection of key analytes such as disease biomarkers, pathogens, neurotransmitters, small molecules, and environmental toxins. Performance metrics, including sensitivity, selectivity, limit of detection, and stability, are discussed in relation to the advantages conferred by the PDA interface. Finally, current challenges, such as optimizing PDA conductivity and long-term stability, and future perspectives, including the development of multiplexed platforms and potential in vivo applications, are addressed.
Indexed as
Identifiers
41739427What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.