ArticleGeroScience2026
Tracking the eyes to track decline: Global eye movement similarity as a novel neuropsychological marker of mild cognitive impairment.
Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionAcross two studies, we investigated whether global eye movement similarity reflects visuospatial memory impairment in older adults, aiming to identify a novel neuropsychological marker of mild cognitive impairment (MCI).
methodsIn Study 1, 35 participants completed a global eye movement similarity memory (GEMS-M) task, viewing indoor scene images with three objects and identifying changes during the recognition phase. In Study 2, 60 participants (30 healthy controls, 30 with MCI) completed a passive version of the task without explicit memory judgment.
resultsStudy 1 showed that the similarity of global eye movement patterns between encoding and recognition phases predicted memory performance, particularly when an object was added. Study 2 demonstrated that global eye movement similarity, combined with demographics, discriminated MCI patients from healthy controls with an AUC of 0.93. DISCUSSION: Our findings suggest that global eye movement similarity may serve as a promising tool for the early detection of MCI.
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