Evidence map›Paper›PMID 41739356›Full record

ArticleInternational journal of computer assisted radiology and surgery2026

Standardizing ACL tunnel placement: an automated method for knee quadrant computation.

Yufan Wang, Zhengliang Li, Yangyang Yang, Yinghui Hua, Tsung-Yuan Tsai

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Article in International journal of computer assisted radiology and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Yufan Wang *School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Huashan Road, Office 224, Shanghai, 200030, China.
Zhengliang Li *School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Huashan Road, Office 224, Shanghai, 200030, China.
Yangyang YangSchool of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Huashan Road, Office 224, Shanghai, 200030, China.
Yinghui HuaDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, China. hua_cosm@aliyun.com.
Tsung-Yuan TsaiSchool of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Huashan Road, Office 224, Shanghai, 200030, China. tytsai@sjtu.edu.cn.ORCID http://orcid.org/0000-0003-1522-2987

Funding

Fundamental Research Funds for Central Universities of the Central South University AF0820060National Natural Science Foundation of China 32371367nnovation Medical Device Application Demonstration Project supported by the Shanghai Municipal Commission of Economy and Informatization, Shanghai Municipal Health Commission, and Shanghai Municipal Medical Security Bureau 23SHS02800-06
6 · The paper itself

Abstract

purposeAnatomical tunnel placement in the anterior cruciate ligament (ACL) reconstruction is essential for better functional recovery and reduced complications. However, subjective factors and ambiguous definitions reduce the accuracy and efficiency of quantifying ACL position on 3D models. This study aims to develop and validate a fully automated framework for standardized 3D quadrant coordinate computation of femoral and tibial ACL footprints, enabling objective preoperative planning and postoperative evaluation.

methodsAn nnUNet-based foundation network was fine-tuned to reconstruct distal femur and proximal tibia 3D models from CT or MRI data. Automated template registration and morphological analysis were used to determine anatomical planes and generate individualized quadrant coordinate systems. The pipeline was validated on both CT and MRI datasets, comparing location accuracy, calculation repeatability, and time efficiency against manual methods.

resultsThe 3D distances between the actual and automatic predicted centroids were 1.72 ± 0.94 mm and 1.47 ± 1.06 mm for femur and tibia, respectively, while the errors of manual method were 1.89 ± 1.42 mm and 2.11 ± 1.27 mm. The method achieved an average repeatability of 0.992 in quadrant calculations with different initializations, while the ICCs of two manual annotation were 0.961 (A), 0.946 (B), and 0.882 (A&B). The processing time for generating quadrant coordinate systems was significantly reduced to an average of 4.7 ± 1.3 s, compared to 8.5 ± 2.1 min for manual annotation.

conclusionThis study presented the first fully automated, modality-independent method for 3D quadrant coordinate computation in knee surgery. The proposed framework delivers robust and standardized ACL anatomical locations across both CT and MRI data, enhancing the clinical efficiency of the preoperative planning and postoperative assessment of ACL reconstruction.

Indexed as

Anterior Cruciate LigamentAnterior Cruciate Ligament ReconstructionImaging, Three-DimensionalKnee JointSurgery, Computer-AssistedTomography, X-Ray ComputedFemurHumansMagnetic Resonance ImagingReproducibility of ResultsTibiaAnterior cruciate ligamentAutomated 3D analysisBlumensaat’s lineComputed tomographyMagnetic resonance imagingQuadrant method

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.