Evidence map›Paper›PMID 41739206›Full record

ArticleChirurgie (Heidelberg, Germany)2026

[Malnutrition in lung cancer patients : Influence of preoperative nutritional status on the postoperative outcome in patients with non-small cell lung cancer (NSCLC) after curative surgery].

T Rabenhold, M Krüger, W Schütte, M Möller, N M Dörr-Jerat

Abstract readEnglish Abstract
In one paragraph

Article in Chirurgie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

T RabenholdKlinik f. Thoraxchirurgie, Krankenhaus Martha-Maria Halle-Dölau, Röntgenstr. 1, 06120, Halle (Saale), Deutschland. t.rabenhold@gmail.com.
M KrügerKlinik f. Thoraxchirurgie, Krankenhaus Martha-Maria Halle-Dölau, Röntgenstr. 1, 06120, Halle (Saale), Deutschland.
W SchütteKlinik f. Thoraxchirurgie, Krankenhaus Martha-Maria Halle-Dölau, Röntgenstr. 1, 06120, Halle (Saale), Deutschland.
M MöllerKlinik f. Thoraxchirurgie, Krankenhaus Martha-Maria Halle-Dölau, Röntgenstr. 1, 06120, Halle (Saale), Deutschland.
N M Dörr-JeratKlinik f. Thoraxchirurgie, Krankenhaus Martha-Maria Halle-Dölau, Röntgenstr. 1, 06120, Halle (Saale), Deutschland. niels.doerr-jerat@martha-maria.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalnutrition poses a significant risk for patients with non-small cell lung cancer (NSCLC). A reduced nutritional status is associated with functional decline and perioperative complications, thereby impairing treatment success and prognosis.

methodsA retrospective single-center cohort study including 197 NSCLC patients who underwent curative surgery between 2015 and 2024 was conducted. The aim was to examine the relationship between preoperative nutritional status, postoperative outcome and long-term prognosis in NSCLC patients.

resultsBased on age-adjusted body mass index (BMI) 28.4% of patients were underweight, 35.5% normal weight and 36.1% overweight. Approximately one third of the patients had a nutritional risk scoring (NRS) ≥ 3 and 65% a Grazer malnutrition screening (GMS) ≥ 3, each indicating a risk of malnutrition. A C-reactive protein-albumin ratio (CAR) ≥ 0.144 was observed in 44.2% of patients. Severe postoperative complications (Clavien-Dindo classification, CDC ≥ °III) were associated with NRS ≥ 3, GMS ≥ 3 and CAR ≥ 0.144. Patients with elevated NRS and GMS scores showed a higher risk of recurrence and mortality. An increase in CAR by 1 was associated with a 41% higher mortality risk.

conclusionThe preoperative nutritional status influenced postoperative outcomes after curative surgery. Given the predictive relevance of individual parameters, nutritional screening should be performed multiparametrically. Further studies are needed to translate these findings into clinical practice and prehabilitation-based nutritional strategies.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsMalnutritionNutritional StatusPostoperative ComplicationsAgedBody Mass IndexFemaleHumansMaleMiddle AgedPreoperative PeriodPrognosisRetrospective StudiesMalnutritionNSCLCNutritional statusPostoperative outcomeSurvival

Identifiers

PMID41739206
PMCPMC13421271

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.