Observational studyIndian journal of ophthalmology2026
Anterior segment optical coherence tomography assessment of Schlemm's canal before and after Descemet membrane endothelial keratoplasty: A retrospective observational study.
Observational study in Indian journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to evaluate Schlemm's canal (SC) parameters using anterior segment optical coherence tomography (AS-OCT) in eyes undergoing Descemet membrane endothelial keratoplasty (DMEK).
designThis is a retrospective, cross-sectional, observational study.
methodsThe study included 22 eyes from 22 patients with pseudophakic bullous keratopathy, with a mean age of 70 ± 11.4 years. AS-OCT (Triton) scans were performed with the patient fixating nasally; horizontal images were obtained from the temporal limbus to visualize SC.
resultsA significant difference was found in visual acuity [1.9 (0.5-2.3) LogMAR vs. 0.5 (0.1-2.3) LogMAR, respectively] and central corneal thickness (CCT) [850 (630-950) µm vs. 545 (407-900) µm, respectively] before and after DMEK surgery (P < 0.01 for both). No significant difference was observed in postoperative intraocular pressure (IOP) [12 (6-20) mmHg] compared to preoperative values [13 (6-18) mmHg] (P = 1.00). There was a significant difference between the preoperative and postoperative SC length (SCL) values (249 µm vs. 266.5 µm, respectively; P < 0.001) as well as SC area (SCA) values (4893.5 µm² vs. 5227 µm², respectively) at the third month (P = 0.001). Changes in CCT and IOP were not significantly correlated with changes in SCA (P = 0.658 vs. P = 0.460) or SCL (P = 0.435 vs. P = 0.377). Tamponade with sulfur hexafluoride (SF₆) or air did not significantly affect preoperative and postoperative SCA (P = 0.974 vs. P = 0.821, respectively) and SCL (P = 0.974 vs. P = 0.792, respectively).
conclusionAS-OCT imaging revealed postoperative expansion of SC parameters following DMEK, with no detectable adverse impact attributable to the surgical procedure or SF₆ use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.