ArticleJACC. Case reports2026
Transcaval SESAME, LAMPOON, and Valve-in-MAC: First Experience With SESAME Outside the United States.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Early Experience With the Septal Scoring Along the Midline Endocardium (SESAME) Technique in the Asia-Pacific Region.JACC. Case reports · 2026Article
- The Next Era of Transcatheter Electrosurgery for Structural Heart Interventions.JACC. Case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe SESAME (SEptal Scoring Along Midline Endocardium) procedure is early in its evolution but seems to be an effective adjunct to facilitate transcatheter mitral valve replacement (TMVR) in patients with complex anatomy. CASE SUMMARY: An 80-year-old woman was admitted with pulmonary edema and diagnosed with severe mitral annular calcification (MAC) and significant mixed mitral disease prohibitive for surgery. She had a history of hypertrophic obstructive cardiomyopathy previously treated with alcohol septal ablation. We performed a SESAME followed by LAMPOON (Laceration of the Anterior Mitral leaflet to Prevent Outflow ObstructioN) to enable a successful transcatheter valve-in-MAC. DISCUSSION: Valve-in-MAC constitutes a high risk for major complications. This case demonstrates an approach with different minimally invasive electrosurgical procedures to enable successful TMVR. TAKE-HOME MESSAGE: The case highlights the importance of collaboration, pre- and intraprocedural imaging, and preparation in order to predict and prevent the risk of iatrogenic left ventricular outflow tract obstruction when performing TMVR in complex patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.