Evidence map›Paper›PMID 41738708›Full record

ArticleTurk gogus kalp damar cerrahisi dergisi2026

Prognostic effect of systemic inflammation in patients undergoing cytoreductive surgery and hyperthermic intrathoracic chemotherapy.

Ahmet Kayahan Tekneci, Hasan Yavuz, Gizem Keçeci Özgür, Tevfik İlker Akçam, Ayşe Gül Ergönül, Kutsal Turhan, Alpaslan Çakan, Ufuk Çağırıcı

Abstract read
In one paragraph

Article in Turk gogus kalp damar cerrahisi dergisi, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ahmet Kayahan TekneciDepartment of Thoracic Surgery, Ege University Faculty of Medicine, İzmir, Türkiye.ORCID 0000-0003-2261-2975
Hasan YavuzClinic of Thoracic Surgery, Mardin Training and Research Hospital, Mardin, Türkiye.ORCID 0000-0001-5641-071X
Gizem Keçeci ÖzgürDepartment of Thoracic Surgery, Acıbadem University Kent Hospital, İzmir, Türkiye.ORCID 0000-0002-9434-4941
Tevfik İlker AkçamDepartment of Thoracic Surgery, Ege University Faculty of Medicine, İzmir, Türkiye.ORCID 0000-0001-7108-9469
Ayşe Gül ErgönülDepartment of Thoracic Surgery, Ege University Faculty of Medicine, İzmir, Türkiye.ORCID 0000-0001-8854-953X
Kutsal TurhanDepartment of Thoracic Surgery, Acıbadem University Kent Hospital, İzmir, Türkiye.ORCID 0000-0003-4150-0514
Alpaslan ÇakanDepartment of Thoracic Surgery, Ege University Faculty of Medicine, İzmir, Türkiye.ORCID 0000-0002-4958-0996
Ufuk ÇağırıcıDepartment of Thoracic Surgery, Ege University Faculty of Medicine, İzmir, Türkiye.ORCID 0000-0001-7827-793X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To investigate prognostic significance of systemic inflammation-related parameters in patients undergoing cytoreductive surgery and hyperthermic intrathoracic chemotherapy for malignant pleural mesothelioma (MPM). Methods: Data from 55 patients were analyzed retrospectively. Demographic characteristics, survival outcomes and inflammation-related parameters (neutrophil/lymphocyte ratio [NLR], platelet/lymphocyte ratio [PLR], lymphocyte/monocyte ratio [LMR] and pan-immune inflammation value [PIV]) were evaluated. Results: Overall survival (OS) was 61.26±13.03 (3-79) months in patients with low NLR, whereas, it was 23.18±3.53 (1-147) months in patients with high NLR (p=0.012). No statistically significant differences in OS were detected according to LMR, PLR and PIV. In addition, OS was 24.40±4.91 (3-92) months in men and 52.8±10.92 (1-147) months in women (p=0.031). Conclusion: In this study, NLR was found to be associated with survival in agreement with the existing literature, thereby distinguishing it from other inflammatory markers as a prognostic factor. In clinical practice, predicting patient prognosis based on pre-treatment NLR may provide a valuable guidance for treatment decision-making.

Indexed as

cytoreductive surgeryHITHOCpleural mesotheliomaprognosisSystemic inflammation

Identifiers

PMID41738708
PMCPMC13051732

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.