Evidence map›Paper›PMID 41738685›Full record

Observational studyEuropean journal of neurology2026

Safety of Physical Activity After Cervical Artery Dissection.

Lukas Mayer-Suess, Josefin Kaufmann, Christopher Traenka, Silvia Felicetti, Sebastian Kaufmann, Benjamin Dejakum, Lukas S Enz, Gudrun Ratzinger, Simon Truessel, Elke R Gizewski and 3 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lukas Mayer-SuessDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria.
Josefin KaufmannDepartment of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland.ORCID 0000-0001-7744-2796
Christopher TraenkaDepartment of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland.ORCID 0000-0002-7600-1005
Silvia FelicettiDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria.
Sebastian KaufmannDepartment of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland.
Benjamin DejakumDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria.ORCID 0009-0002-9954-9687
Lukas S EnzDepartment of Clinical Research, University of Basel, Basel, Switzerland.
Gudrun RatzingerDepartment of Dermatology, Venereology and Allergology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria.
Simon TruesselDepartment of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland.
Elke R GizewskiDepartment of Radiology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria.ORCID 0000-0001-6859-8377
Stefan KiechlDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria.
Stefan EngelterDepartment of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland.
Michael KnoflachDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria.

Funding

Oesterreichische Nationalbank 15644Österreichische Forschungsförderungsgesellschaft 898252
6 · The paper itself

Abstract

backgroundCervical artery dissection (CeAD) is a major cause for stroke in young adults. A timely association with minor-to-moderate unimposing cervical trauma, which is often sports-related, is common in CeAD. Our goal was to assess whether physical activity puts patients at risk post-CeAD.

methodsPooled data from two prospective observational CeAD cohorts with in-person follow-up of at least 1-year post-CeAD were assessed. Changes in physical activity were recorded using patient-reported assessment of change in activity compared to pre-CeAD. Baecke score-derived sports index was applied to address the association between physical activity intensity and our outcomes. Outcomes were (1) recurrent dissection and (2) cerebral ischemia upon follow-up.

resultsA total of 648 CeAD patients were recorded. Physical activity-specific follow-up data were available in 333 (59.7%). The median follow-up duration was 6.5 (IQR 3.1, 10.9) years with 17/333 (5.1%) suffering CeAD recurrence and 22/33#3 (6.6%) experiencing cerebral ischemia. A total of 197 of 333 (59.2%) patients reported a change in physical activity post-CeAD (127 [64.5%] decrease, 70 [35.5%] increase). Neither overall change, increase, or decrease of physical activity was associated with recurrent CeAD or cerebral ischemia (p > 0.2 throughout). However, regular performance of higher-intensity sports, assessed via Baecke score-derived sports index, associated in trend to dissection recurrence (OR 3.43 [0.86, 13.64]; p = 0.080).

conclusionsCeAD patients should be reassured that regaining physical activity after CeAD is safe. However, moderation on exertion should be discussed on an individual patient basis.

Indexed as

Carotid Artery, Internal, DissectionExerciseVertebral Artery DissectionAdultBrain IschemiaDissection, Blood VesselFemaleFollow-Up StudiesHumansMaleMiddle AgedRecurrencecervical artery dissectionoutcomephysical activityrecurrencesportsstroke

Identifiers

PMID41738685
PMCPMC12933877

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.