Evidence map›Paper›PMID 41738279›Full record

ArticleAmerican journal of respiratory and critical care medicine2026

High tPA activity but absent PAI-1 and plasminogen function early in intrapleural lytic therapy.

Elizabeth R Maginot, Peter K Moore, Cesar Davila-Chapa, Jiashan Wang, Henry Kramer, Christopher J King, Joseph J Mcbride, Reynold Henry, Daniel Hershberger, Christopher D Barrett and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elizabeth R MaginotDivision of Acute Care Surgery, Department of Surgery, University of Nebraska Medical Center, Omaha, NE, United States.
Peter K MooreDivision of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Cesar Davila-ChapaDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, United States.
Jiashan WangDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, United States.
Henry KramerDivision of Hospital Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Christopher J KingDivision of Hospital Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Joseph J McbrideDepartment of Radiology, University of Nebraska Medical Center, Omaha, NE, United States.
Reynold HenryDivision of Acute Care Surgery, Department of Surgery, University of Nebraska Medical Center, Omaha, NE, United States.
Daniel HershbergerDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, United States.
Christopher D BarrettDivision of Acute Care Surgery, Department of Surgery, University of Nebraska Medical Center, Omaha, NE, United States.
PLUTO Study Group

Funding

Using Patient-Reported Outcomes, Inflammatory Profiles, and Cardiovascular Phenogroups to Expand the Definition of Heart Failure with Preserved Ejection FractionP20GM152326 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Jason Rhede Cook · 2024 to 2026
$10.3M
Mechanisms of Complement Activation in Traumatic InjuryK08HL171936 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Christopher David Barrett · 2024 to 2026
$500k
Francis Family Foundation: Parker B Francis FellowshipNational Heart Lung and Blood Institute K08-HL171936NHLBI NIH HHS K08 HL171936NIGMS NIH HHS P20 GM152326NIGMS NIH HHS P20-GM152326Shock Society Faculty Research AwardUniversity of Colorado Department of Medicine
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41738279
PMCPMC13160939

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.